{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T04:48:42Z","timestamp":1791607722867,"version":"4.3.4"},"reference-count":53,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T00:00:00Z","timestamp":1764115200000},"content-version":"vor","delay-in-days":329,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["12572368"],"award-info":[{"award-number":["12572368"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82405535"],"award-info":[{"award-number":["82405535"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003392","name":"Natural Science Foundation of Fujian Province","doi-asserted-by":"publisher","award":["2025E3005"],"award-info":[{"award-number":["2025E3005"]}],"id":[{"id":"10.13039\/501100003392","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008021","name":"Fujian University of Traditional Chinese Medicine","doi-asserted-by":"publisher","award":["XGS2024004"],"award-info":[{"award-number":["XGS2024004"]}],"id":[{"id":"10.13039\/501100008021","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004387","name":"Ningbo University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004387","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Applied Bionics and Biomechanics"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Gait variability in kinematic and kinetic parameters during stair walking is a key indicator of motor function and fall risk in individuals with knee osteoarthritis (KOA). However, normative reference data and pathological patterns in KOA remain under explored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross\u2010sectional study analyzed retrospective data from 169 participants, including 116 individuals with KOA and 53 matched healthy controls. Each participant performed both stair ascent and descent tasks, during which lower limb kinematic and kinetic gait parameters were obtained using a three\u2010dimensional motion capture (3DMC) system and an instrumented staircase. Intrasubject variability, quantified by coefficient of variation (CV), was calculated for all gait parameters. A mixed between\u2013within subject analysis of variance with aligned rank transformed data was conducted to assess the effects of group (KOA vs. control), condition (stair ascent vs. descent), and their interaction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Individuals with KOA exhibited significantly greater kinematic variability during both stair ascent and descent, whereas greater kinetic variability was observed only in knee and hip joint moments and powers during ascent. Across both groups, variability increased at the knee and distal segments, but decreased at proximal segments (hip and pelvis) during stair ascent compared with descent. KOA individuals displayed distinct adaptation mechanism between stair ascent and descent, but not in kinematic parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Individuals with KOA demonstrate significantly increased movement variability compared with healthy controls during stair walking, especially in knee and hip joint moments and powers during ascent. These findings indicates distinct and task\u2010specific adaptation strategies in KOA, reflecting altered stability and joint loading mechanisms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/abb\/6678937","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T07:19:49Z","timestamp":1764227989000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Intrasubject Gait Variability During Stair Walking in Knee Osteoarthritis: A Kinematic and Kinetic Analysis"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1964-045X","authenticated-orcid":false,"given":"Ye","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9014-2267","authenticated-orcid":false,"given":"Shixin","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-3225-1831","authenticated-orcid":false,"given":"Yaqi","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8222-5179","authenticated-orcid":false,"given":"Chenyi","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0697-0548","authenticated-orcid":false,"given":"Dongwei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4830-5615","authenticated-orcid":false,"given":"Meijin","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,26]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00208-7"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2014.44"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/1759720X241273009"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2020.08.009"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1302\/2058-5241.1.000051"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/9757369"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22015"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2025.1562936"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2024.12.001"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9290(01)00036-7"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2009.08.005"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/jor.20496"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2009.02.001"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.1186\/1743-0003-2-19"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/1743-0003-2-21"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2004.01.014"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-012-1965-y"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2016.08.024"},{"key":"e_1_2_11_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2007.05.016"},{"key":"e_1_2_11_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.wad.0000201849.75578.de"},{"key":"e_1_2_11_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2008.10.061"},{"key":"e_1_2_11_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2015.07.063"},{"key":"e_1_2_11_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelekin.2011.07.011"},{"key":"e_1_2_11_24_2","doi-asserted-by":"publisher","DOI":"10.1589\/jpts.34.140"},{"key":"e_1_2_11_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2015.03.007"},{"key":"e_1_2_11_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2005.06.003"},{"key":"e_1_2_11_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2022.04.022"},{"key":"e_1_2_11_28_2","doi-asserted-by":"publisher","DOI":"10.3109\/09638288.2013.829526"},{"key":"e_1_2_11_29_2","doi-asserted-by":"publisher","DOI":"10.21037\/atm-20-4665"},{"key":"e_1_2_11_30_2","doi-asserted-by":"publisher","DOI":"10.1080\/026404100446775"},{"key":"e_1_2_11_31_2","doi-asserted-by":"publisher","DOI":"10.3390\/s20071903"},{"key":"e_1_2_11_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0268-0033(97)00041-7"},{"key":"e_1_2_11_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0966-6362(01)00162-X"},{"key":"e_1_2_11_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.measurement.2022.111344"},{"key":"e_1_2_11_35_2","doi-asserted-by":"publisher","DOI":"10.1002\/9780470549148"},{"key":"e_1_2_11_36_2","first-page":"155","volume-title":"Coefficient of Variation","author":"Brown C. E.","year":"1998"},{"key":"e_1_2_11_37_2","doi-asserted-by":"publisher","DOI":"10.1145\/1978942"},{"key":"e_1_2_11_38_2","unstructured":"StreamerJ. E. Exploration of Movement Variability and Limb Loading Asymmetry During Simulated Daily Functional Tasks PhD thesis 2022 Virginia Tech."},{"key":"e_1_2_11_39_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-017-8634-5"},{"key":"e_1_2_11_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2009.10.002"},{"key":"e_1_2_11_41_2","article-title":"Gait Variability and Biomechanical Distinctions in Knee Osteoarthritis: Insights from a 3D Analysis in an Adult Elderly Cohort","author":"Tanpure S.","year":"2023","journal-title":"Journal of Orthopaedics"},{"key":"e_1_2_11_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2010.09.024"},{"key":"e_1_2_11_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.humov.2007.05.003"},{"key":"e_1_2_11_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/0167-9457(84)90005-8"},{"key":"e_1_2_11_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(90)90184-O"},{"key":"e_1_2_11_46_2","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.2001.90.6.2117"},{"key":"e_1_2_11_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(02)03332-5"},{"key":"e_1_2_11_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelekin.2010.08.005"},{"key":"e_1_2_11_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2006.09.010"},{"key":"e_1_2_11_50_2","doi-asserted-by":"publisher","DOI":"10.1115\/1.4037791"},{"key":"e_1_2_11_51_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.bor.0000240365.16842.4e"},{"key":"e_1_2_11_52_2","doi-asserted-by":"publisher","DOI":"10.1123\/jab.16.4.419"},{"key":"e_1_2_11_53_2","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0b013e3181dd902e"}],"container-title":["Applied Bionics and Biomechanics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/abb\/6678937","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/abb\/6678937","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/abb\/6678937","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T21:40:09Z","timestamp":1773006009000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/abb\/6678937"}},"subtitle":[],"editor":[{"given":"Guowu","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":53,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/abb\/6678937"],"URL":"https:\/\/doi.org\/10.1155\/abb\/6678937","archive":["Portico"],"relation":{},"ISSN":["1176-2322","1754-2103"],"issn-type":[{"value":"1176-2322","type":"print"},{"value":"1754-2103","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2025-06-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"6678937"}}