{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T06:27:57Z","timestamp":1786688877776,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"vor","delay-in-days":224,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advances in Urology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To compare Holmium: YAG laser settings for popcorn lithotripsy and evaluate the impact of MOSES modulation across stone\u2010density groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>An in vitro bench model was used with synthetic gypsum stones prepared at three density levels (low, intermediate, and high: mean attenuation was 574, 945, and 2067 HU, respectively). For each trial, five fragments (2.8\u20133.3\u2009mm) were treated using popcorn technique with Holmium: YAG laser and 272\u2009\u00b5m fiber during a 2\u2009min run under standardized irrigation. Five laser settings (0.3\u2009J\/80\u2009Hz, 0.5\u2009J\/40\u2009Hz, 1.0\u2009J\/20\u2009Hz, 1.0\u2009J\/30\u2009Hz, and 1.5\u2009J\/20\u2009Hz) were tested with and without MOSES mode: each setting\u2010by\u2010modulation condition was repeated six times. The primary endpoint was percent mass reduction; secondary endpoints were residual fragment counts 1\u20132 and &gt;\u20092\u2009mm. Results are presented as mean\u2009\u00b1\u2009SD, and ANOVA was used for comparison.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In the low\u2010density group, percent mass reduction was highest overall (65%\u201386%), with 1.0\u2009J\/30\u2009Hz achieving the greatest reduction, MOSES provided no additional benefit (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.6). In the intermediate\u2010density group, the greatest mass reduction was achieved with 1.0\u2009J\/30\u2009Hz with MOSES (51%\u2009\u00b1\u20095.9%), and MOSES effects were setting\u2010dependent, and at 1.0\u2009J\/30\u2009Hz MOSES reduced total residual fragments (5.3 vs 8.0,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.04). In the high\u2010density group, 1.0\u2009J\/30\u2009Hz with MOSES achieved the highest mass reduction (71.5%\u2009\u00b1\u200912.1%) and was associated with improved outcomes (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.037). Secondary analyses of residual fragments generally paralleled these findings.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this in vitro popcorn lithotripsy model, 1.0\u2009J\/30\u2009Hz provided the most consistent performance across density groups. MOSES modulation did not improve outcomes in low\u2010density stones but was associated with improved efficiency in intermediate\u2010 and high\u2010density stones.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/aiu\/3584394","type":"journal-article","created":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T05:40:47Z","timestamp":1786686047000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Holmium: YAG Popcorn Lithotripsy\u2014In Vitro Comparison of Settings and MOSES Across Stone Densities"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-1651-2344","authenticated-orcid":false,"given":"Oleksandr","family":"Chepeliuk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3688-5133","authenticated-orcid":false,"given":"Asaf","family":"Shvero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7605-4684","authenticated-orcid":false,"given":"Rinat","family":"Lasmanovich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lopez Isaias","family":"Caballero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dina","family":"Orkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9005-2992","authenticated-orcid":false,"given":"A. Zohar","family":"Dotan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2092-4732","authenticated-orcid":false,"given":"E. Dorit","family":"Zilberman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nir","family":"Kleinmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,13]]},"reference":[{"key":"e_1_2_10_1_2","volume-title":"EAU Guidelines on Urolithiasis. Edn. 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