{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T10:44:21Z","timestamp":1789469061060,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"vor","delay-in-days":257,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advances in Urology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Prostate cancer (PC) is a common male malignancy, and it is often diagnosed at advanced stages, particularly in developing countries, largely due to underdeveloped healthcare systems. Resource\u2010limited care, such as bilateral orchidectomy for symptomatic illness, is an economically feasible therapeutic option that may enhance patient condition and survival in a low\u2010resource situation. This study aims to assess the status of PC care and treatment outcomes in eastern Sudan.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective hospital\u2010based study was conducted at the East Oncology Centre (EOC), Gadarif State, eastern Sudan, including all patients diagnosed with PC between May 2016 and December 2023. Relevant demographic, clinical, pathological, treatment, and outcome data were retrieved from patients\u2019 medical records.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 231 patients with PC, with a mean age of 70.9\u2009years (\u00b1 SD 10), all of whom were Sudanese from different ethnic groups, were included in the study. Most patients (86.6%;\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009200) presented with lower urinary tract symptoms, and only 15.6% had a family history of PC. Most of the patients (62.34%,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009144) had prostate\u2010specific antigen (PSA) levels ranging from 21 to 100\u2009ng\/mL; histopathology revealed adenocarcinoma of the prostate with a Gleason score of 8 or more in 60.6% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009140). Bone scan results were positive in 50.2% of cases, and 88.3% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009204) received hormonal treatment as the primary modality for cancer control. The mortality data indicate that 24.7% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200957) of patients had died.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study highlights the suboptimal care for PC in eastern Sudan, where most patients present with late\u2010stage disease, probably due to resource limitations. Addressing late\u2010stage PC requires opportunistic digital rectal examination screening, targeted PSA testing, and increased awareness. Improved outcomes rely on specialist training, standardised care protocols, and the expansion of radiation facilities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/aiu\/3967008","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T09:30:14Z","timestamp":1789464614000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessing the Level of Prostate Cancer Care in a Low\u2010Resource Setting: Disease Pattern, Current Situation of Care, and the Need for Reform\u2014A Retrospective Observational Study From East Oncology Centre, Sudan"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0750-6306","authenticated-orcid":false,"given":"Mosab A. 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