{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T05:55:04Z","timestamp":1781502904618,"version":"3.54.1"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"vor","delay-in-days":57,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advances in Urology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To explore the predictive value of serum cystatin C (CysC) for contrast\u2010induced acute kidney injury (CI\u2010AKI) in elderly individuals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The study included 102 elderly patients (80\u2009years) who underwent percutaneous coronary interventions at the Fourth People\u2019s Hospital of Shanghai Affiliated to Tongji University between September 2020 and January 2024. Based on their diagnosis, they were divided into those with CI\u2010AKI (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200910) and those without CI\u2010AKI (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200992). A fully automated biochemical analyzer was used to measure the serum CysC levels at baseline and 48\u2009h after coronary angiography or percutaneous coronary intervention in the two groups, and the association of serum CysC levels and other relevant clinical indicators with the occurrence of CI\u2010AKI was evaluated to determine the predictive value of baseline serum CysC for diagnosing contrast agent\u2010induced nephropathy based on receiver operating characteristic curves.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Age, serum CysC, and serum creatinine levels were significantly higher in the CI\u2010AKI group than in the non\u2010CI\u2010AKI group. Serum CysC was found to be a predictor of CI\u2010AKI based on an area under the curve of 0.731 (95% confidence interval\u2009=\u20090.569\u20130.893).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The occurrence of contrast\u2010induced nephropathy is related to age, serum CysC, and serum creatinine levels. In particular, serum CysC had high predictive value for CI\u2010AKI in those aged above 80\u2009years.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/aiu\/9478896","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:41:08Z","timestamp":1773013268000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prognostic Value of Serum Cystatin C for Predicting Contrast\u2010Induced Nephropathy in Elderly Individuals Aged Over 80\u2009Years"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-6680-258X","authenticated-orcid":false,"given":"Xiangxiang","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1963-7735","authenticated-orcid":false,"given":"Zhixiang","family":"Bian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4154-5288","authenticated-orcid":false,"given":"Rui","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2464-9538","authenticated-orcid":false,"given":"Shunjie","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,27]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26072869"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.issn.0376-2491.2019.40.002"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2016.08.034"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1159\/000485341"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.19193\/0393-6384_2022_1_84"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfaa142.P0609"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.11622\/smedj.2021002"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/CM9.0000000000000641"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.5644\/ama2006-124.184"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.3969\/j.issn.1672-5921.2014.12.002"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.31729\/jnma.8065"},{"key":"e_1_2_10_12_2","doi-asserted-by":"publisher","DOI":"10.4103\/1319-2442.225199"},{"key":"e_1_2_10_13_2","doi-asserted-by":"publisher","DOI":"10.5301\/jn.5000101"},{"key":"e_1_2_10_14_2","doi-asserted-by":"publisher","DOI":"10.26442\/00403660.2020.10.000753"},{"key":"e_1_2_10_15_2","doi-asserted-by":"publisher","DOI":"10.1080\/00015385.2021.1901022"},{"key":"e_1_2_10_16_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.21876"},{"key":"e_1_2_10_17_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-020-01570-6"},{"key":"e_1_2_10_18_2","doi-asserted-by":"publisher","DOI":"10.4103\/1319-2442.393994"}],"updated-by":[{"DOI":"10.1155\/aiu\/9824973","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2026,6,14]],"date-time":"2026-06-14T00:00:00Z","timestamp":1781395200000}}],"container-title":["Advances 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