{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T20:12:17Z","timestamp":1773000737952,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T00:00:00Z","timestamp":1736294400000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anemia"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    The effect of pretransfusion hemoglobin on transfusion burden, thrombosis, and mortality in thalassemia and myelodysplastic syndrome is unclear. We aimed to study the pretransfusion hemoglobin and erythrocyte transfusion burden and investigate the effects of these variables on each other in real\u2010life in thalassemia and myelodysplastic syndrome. Adult patients with thalassemia and myelodysplastic syndrome who received at least one erythrocyte concentrate unit outpatient at Sanliurfa Mehmet Akif Inan Training and Research Hospital during 1\u2009year were included in the study. The data were retrospectively obtained. Ethical approval was obtained for the study. Ninety\u2010two patients were included in the study. In thalassemia major, pretransfusion hemoglobin \u2265 9\u2009g\/dL was associated with a lower median annual number of transfused erythrocyte concentrate units (15 vs. 27) and median annual number of transfusion sessions (11 vs. 14)\n                    <jats:italic>p<\/jats:italic>\n                    = 0.002,\n                    <jats:italic>p<\/jats:italic>\n                    = 0.009, respectively). In myelodysplastic syndrome, a pretransfusion hemoglobin level \u2265 8\u2009g\/dL was associated with a lower median annual number of transfused erythrocyte concentrate units (6 vs. 24) (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.016). In thalassemia major with an intact spleen, pretransfusion hemoglobin \u2265 8\u2009g\/dL was associated with an increased median annual number of transfused erythrocyte concentrate units (32 vs. 27) and median annual number of transfusion sessions (18 vs. 14) (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.046,\n                    <jats:italic>p<\/jats:italic>\n                    = 0.038, respectively). In conclusion, higher pretransfusion hemoglobin levels were related to a lower transfusion burden in thalassemia major and myelodysplastic syndrome.\n                  <\/jats:p>","DOI":"10.1155\/anem\/7257391","type":"journal-article","created":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T04:38:46Z","timestamp":1736311126000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Real Life Blood Management Practices in Thalassemia and Myelodysplastic Syndrome Patients"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7991-5275","authenticated-orcid":false,"given":"Muruvvet S.","family":"Aydin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8583-778X","authenticated-orcid":false,"given":"Esra","family":"Cengiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,1,8]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1182\/hematology.2020000102"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2023.101138"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.18671"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2019.01.003"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41408-022-00765-8"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1182\/hematology.2020000103"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.3390\/curroncol30070459"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/hs9.0000000000000732"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-019-03065-5"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/mgg3.1788"},{"key":"e_1_2_9_11_2","unstructured":"Hasta Kan Y\u00f6netimi Rehberi Modul 3-Dahili Hastaliklar.Pdf 2023 https:\/\/dosyamerkez.saglik.gov.tr\/Eklenti\/44848\/0\/3-hasta-kan-yonetimi-rehberi-modul-3---dahili-hastaliklarpdf.pdf."},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2023022460"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.16392"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.17612"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-03-420489"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2023020683"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2019.100588"},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.2450\/2012.0012-12"},{"key":"e_1_2_9_19_2","doi-asserted-by":"publisher","DOI":"10.1080\/16078454.2020.1856513"},{"key":"e_1_2_9_20_2","doi-asserted-by":"publisher","DOI":"10.5045\/br.2023.2023009"},{"key":"e_1_2_9_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.16347"},{"key":"e_1_2_9_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/trf.17721"},{"key":"e_1_2_9_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16946"},{"key":"e_1_2_9_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cll.2023.07.002"},{"key":"e_1_2_9_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40266-021-00881-3"}],"container-title":["Anemia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/anem\/7257391","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/anem\/7257391","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/anem\/7257391","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T17:44:50Z","timestamp":1772991890000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/anem\/7257391"}},"subtitle":[],"editor":[{"given":"Shamreen","family":"Naaz","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/anem\/7257391"],"URL":"https:\/\/doi.org\/10.1155\/anem\/7257391","archive":["Portico"],"relation":{},"ISSN":["2090-1267","2090-1275"],"issn-type":[{"value":"2090-1267","type":"print"},{"value":"2090-1275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2024-05-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"7257391"}}