{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T07:22:53Z","timestamp":1787556173667,"version":"build-2736575974"},"reference-count":44,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T00:00:00Z","timestamp":1787529600000},"content-version":"vor","delay-in-days":235,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Treatment"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Dyslipidemia is a common metabolic complication among people living with HIV and a major contributor to cardiovascular morbidity and mortality. However, it remains insufficiently characterized in Ethiopia, particularly in contemporary urban ART settings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We conducted a facility\u2010based cross\u2010sectional study among 398 patients selected by systematic random sampling from November 1 to December 31, 2025. Data were collected using a structured data collection tool, entered into KoboToolbox, and analyzed in SPSS Version 27. Bivariable and multivariable logistic regression analyses were used to identify factors associated with dyslipidemia. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated, and\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05 was considered statistically significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The median age of participants was 50\u2009years (IQR: 42\u201356), and 66.8% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009266) were female. The median duration since HIV diagnosis was 19\u2009years (IQR: 15\u201320). Predominant regimens included TDF+3TC+\u2009DTG (72.8%). The prevalence of dyslipidemia was 65.3% (95% CI: 60.5\u201370.1), with elevated triglycerides (37.2%), total cholesterol (34.7%), high LDL\u2010C (34.2%), and low HDL\u2010C (28.1%). On multivariable analysis, dyslipidemia was significantly associated with history of ART change (AOR 2.62, 95% CI: 1.13\u20136.04), hypertension (AOR 2.45, 95% CI: 1.28\u20134.69), overweight (AOR 3.56, 95% CI: 1.44\u20138.81), obesity (AOR 5.15, 95% CI: 1.16\u201322.82), and sedentary and moderate physical activity (AOR 9.46, 95% CI: 2.46\u201336.32 and AOR 3.80, 95% CI: 1.77\u20138.18, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Dyslipidemia was prevalent among approximately two in three HIV\u2010positive patients receiving long\u2010term ART at two tertiary hospitals in Addis Ababa, Ethiopia. These findings highlight the need for routine lipid monitoring and integrated cardiovascular risk management within HIV care settings in similar urban, tertiary\u2010care contexts.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/arat\/9582674","type":"journal-article","created":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T07:06:22Z","timestamp":1787555182000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence and Correlates of Dyslipidemia in HIV\u2010Positive Patients at Selected Public Hospitals in Addis Ababa, Ethiopia, 2025"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-3264-5572","authenticated-orcid":false,"given":"Nebiat","family":"Adane","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2977-5606","authenticated-orcid":false,"given":"Mekoya","family":"Mengistu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tariku","family":"Fekadu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2688-6198","authenticated-orcid":false,"given":"Abraham Tekola","family":"Gebremedhn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahder Abebe","family":"Asres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4213-8142","authenticated-orcid":false,"given":"Nevena","family":"Ivanova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1974-913X","authenticated-orcid":false,"given":"Subah Abderehim","family":"Yesuf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,24]]},"reference":[{"key":"e_1_2_14_1_2","article-title":"Obesity, Dyslipidemia, and Cardiovascular Disease: A Joint Expert Review From the Obesity Medicine Association and the National Lipid Association 2024","volume":"10","author":"Bays H. E.","year":"2024","journal-title":"Obes Pillars"},{"key":"e_1_2_14_2_2","doi-asserted-by":"publisher","DOI":"10.2174\/1874192401105010049"},{"key":"e_1_2_14_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecl.2014.06.003"},{"key":"e_1_2_14_4_2","doi-asserted-by":"publisher","DOI":"10.3390\/life14040449"},{"key":"e_1_2_14_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2023.102255"},{"key":"e_1_2_14_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2020.02.004"},{"key":"e_1_2_14_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/cm9.0000000000002879"},{"key":"e_1_2_14_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2024.05.004"},{"key":"e_1_2_14_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacl.2023.05.099"},{"key":"e_1_2_14_10_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu17050776"},{"key":"e_1_2_14_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2026.104763"},{"key":"e_1_2_14_12_2","first-page":"1","article-title":"The Path That Ends AIDS: UNAIDS Global AIDS Update 2023","volume":"11","author":"Joint United Nations Programme on HIV\/AIDS (UNAIDS)","year":"2023","journal-title":"Joint United Nations Programme on HIV\/AIDS"},{"key":"e_1_2_14_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-023-08910-9"},{"key":"e_1_2_14_14_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0298525"},{"key":"e_1_2_14_15_2","doi-asserted-by":"publisher","DOI":"10.1155\/arat\/6621097"},{"key":"e_1_2_14_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2025.120487"},{"key":"e_1_2_14_17_2","doi-asserted-by":"publisher","DOI":"10.4093\/dmj.2022.0198"},{"key":"e_1_2_14_18_2","volume-title":"Addis Ababa Population 2025","author":"World Population Review","year":"2025"},{"key":"e_1_2_14_19_2","doi-asserted-by":"publisher","DOI":"10.1086\/378131"},{"key":"e_1_2_14_20_2","doi-asserted-by":"crossref","DOI":"10.1186\/s12872-025-04887-2","article-title":"Optimizing Statin Therapy in HIV-Infected","volume":"25","author":"Ansari R.","year":"2025","journal-title":"BMC Cardiovascular Disorders"},{"key":"e_1_2_14_21_2","doi-asserted-by":"crossref","DOI":"10.1093\/ehjopen\/oeae032","article-title":"Dyslipidaemia Management in Pregnant Patients: A 2024 Update","volume":"4","author":"Lewek J.","year":"2024","journal-title":"European Heart Journal Open"},{"key":"e_1_2_14_22_2","doi-asserted-by":"publisher","DOI":"10.2147\/dhps.s395037"},{"key":"e_1_2_14_23_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2025.1506149"},{"key":"e_1_2_14_24_2","unstructured":"WHO Body Mass Index (BMI) 2026 https:\/\/www.who.int."},{"key":"e_1_2_14_25_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-024-18468-z"},{"key":"e_1_2_14_26_2","first-page":"1451","article-title":"World Health Organization 2020 Guidelines on Physical Activity and Sedentary Behaviour","volume":"54","author":"Bull F. C.","year":"2020","journal-title":"Sports Medicine"},{"key":"e_1_2_14_27_2","doi-asserted-by":"publisher","DOI":"10.1097\/cm9.0000000000003336"},{"key":"e_1_2_14_28_2","doi-asserted-by":"publisher","DOI":"10.37432\/jieph.2023.6.1.76"},{"key":"e_1_2_14_29_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0270838"},{"key":"e_1_2_14_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.obmed.2020.100217"},{"key":"e_1_2_14_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2022.e11342"},{"key":"e_1_2_14_32_2","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/1578653"},{"key":"e_1_2_14_33_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-023-08892-8"},{"key":"e_1_2_14_34_2","doi-asserted-by":"publisher","DOI":"10.2147\/hiv.s529826"},{"key":"e_1_2_14_35_2","doi-asserted-by":"publisher","DOI":"10.5812\/ijem.4783"},{"key":"e_1_2_14_36_2","doi-asserted-by":"publisher","DOI":"10.4236\/ojim.2019.94019"},{"key":"e_1_2_14_37_2","doi-asserted-by":"publisher","DOI":"10.1177\/23259582251395549"},{"key":"e_1_2_14_38_2","volume-title":"Virologic and Immunologic Monitoring in HIV Care","author":"Peddireddy S. P.","year":"2025"},{"key":"e_1_2_14_39_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2024.1425414"},{"key":"e_1_2_14_40_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11883-023-01132-z"},{"key":"e_1_2_14_41_2","doi-asserted-by":"publisher","DOI":"10.4103\/2230-8210.93742"},{"key":"e_1_2_14_42_2","volume-title":"Adipose Tissue Dysfunction and Energy Balance Paradigms in People Living With HIV","author":"Bustamante C. E. R.","year":"2023"},{"key":"e_1_2_14_43_2","doi-asserted-by":"crossref","DOI":"10.11599\/germs.2015.1072","article-title":"The Role of Adipokines in HIV Lipodystrophy","volume":"5","author":"Dragovi\u0107 G.","year":"2015","journal-title":"GERMS"},{"key":"e_1_2_14_44_2","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.2147\/PPA.S360517","article-title":"Physical Activities and Associated Factors Among HIV\/AIDS Patients: A Questionnaire Survey","author":"Zou Y.","year":"2022","journal-title":"Patient Prefer Adherence"}],"container-title":["AIDS Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/arat\/9582674","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/arat\/9582674","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/arat\/9582674","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T07:06:25Z","timestamp":1787555185000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/arat\/9582674"}},"subtitle":[],"editor":[{"given":"Suraiya","family":"Saleem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":44,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/arat\/9582674"],"URL":"https:\/\/doi.org\/10.1155\/arat\/9582674","archive":["Portico"],"relation":{},"ISSN":["2090-1240","2090-1259"],"issn-type":[{"value":"2090-1240","type":"print"},{"value":"2090-1259","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2026-04-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"9582674"}}