{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T12:10:41Z","timestamp":1779019841985,"version":"3.51.4"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:00:00Z","timestamp":1778544000000},"content-version":"vor","delay-in-days":131,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                      and\n                      <jats:italic>Enterococcus faecalis<\/jats:italic>\n                      are bacteria for which new antibiotics are urgently needed.\n                      <jats:italic>Corryocactus brevistylus<\/jats:italic>\n                      is a Peruvian cactus with an antibacterial effect that has not yet been studied.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To determine the antibacterial effect of\n                      <jats:italic>C. brevistylus<\/jats:italic>\n                      methanol extract against\n                      <jats:italic>S. aureus<\/jats:italic>\n                      (ATCC 6538) and\n                      <jats:italic>E. faecalis<\/jats:italic>\n                      (ATCC 29212).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Sanky fruits were extracted with methanol (1:2,\n                      <jats:italic>w<\/jats:italic>\n                      \/\n                      <jats:italic>v<\/jats:italic>\n                      ). Agar well diffusion tests were used by preparing wells with the experimental solutions cultivated in aerobic conditions for 24\u2009h at 37\u00b0C. Six independent tests were prepared for each type of bacteria, using penicillin\u2013streptomycin and chlorhexidine as positive controls. The MIC was determined using the microdilution method as described by the CLSI.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The antibacterial effect of the methanol extract was dose\u2010dependent, with inhibition zones of 23.33 \u00b1 0.72 and 24.34 \u00b1 0.55\u2009mm against\n                      <jats:italic>S. aureus<\/jats:italic>\n                      and\n                      <jats:italic>E. faecalis<\/jats:italic>\n                      , respectively, at the highest concentration. Meanwhile, penicillin\u2013streptomycin (10\u2009U) and chlorhexidine produced inhibition zones comparable to the extract at the highest concentration. The MIC achieved by the extract was 15.6\u2009mg\/mL for both\n                      <jats:italic>S. aureus<\/jats:italic>\n                      and\n                      <jats:italic>E. faecalis<\/jats:italic>\n                      , while the MBC for\n                      <jats:italic>S. aureus<\/jats:italic>\n                      was 62.5\u2009mg\/mL and for E.\n                      <jats:italic>faecalis<\/jats:italic>\n                      31.3\u2009mg\/mL.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Weak antibacterial potency was observed in the methanolic extract of\n                      <jats:italic>C. brevistylus<\/jats:italic>\n                      against the strains of\n                      <jats:italic>S. aureus<\/jats:italic>\n                      and\n                      <jats:italic>E. faecalis<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/bmri\/1496244","type":"journal-article","created":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T11:59:01Z","timestamp":1778587141000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Antibacterial Activity of\n                    <i>Corryocactus brevistylus<\/i>\n                    (Sanky) Methanolic Extract Against\n                    <i>Staphylococcus aureus<\/i>\n                    and\n                    <i>Enterococcus faecalis<\/i>"],"prefix":"10.1155","volume":"2026","author":[{"given":"Ronald","family":"Aquino-Ortega","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugo","family":"Carrillo-Ng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luz 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