{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T11:24:49Z","timestamp":1787225089863,"version":"build-2736575974"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"vor","delay-in-days":231,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Oxidative stress is a major contributor to the development of various chronic illnesses, making the evaluation of plant\u2010derived antioxidants a crucial step in the search for novel therapeutic agents.\n                    <jats:italic>Glycosmis cyanocarpa<\/jats:italic>\n                    (Blume) Spreng., a relatively underexplored species native to South and Southeast Asia, has shown potential as a natural antioxidant source. Therefore, the current study aimed to assess the antioxidant potential of the crude methanolic extract of\n                    <jats:italic>G. cyanocarpa<\/jats:italic>\n                    (GCM) by determining its total phenolic content (TPC), total flavonoid content (TFC), evaluating its free radical scavenging and reducing power through DPPH, ABTS, and FRAP assays, and conducting Pearson\u2019s correlation analysis to explore the associations among these parameters. The extract exhibited a TPC of 44.84 \u00b1 0.99\u2009mg gallic acid equivalent\/g and a TFC of 60.83 \u00b1 2.60\u2009mg quercetin equivalent\/g. GCM demonstrated significant antioxidant activity with IC\n                    <jats:sub>50<\/jats:sub>\n                    values of 18.80 \u00b1 0.42\u2009\n                    <jats:italic>\u03bc<\/jats:italic>\n                    g\/mL in DPPH and 74.54 \u00b1 0.31\u2009\n                    <jats:italic>\u03bc<\/jats:italic>\n                    g\/mL in ABTS assays, and a ferric reducing capacity of 2.42 \u00b1 0.33\u2009mmol Fe\n                    <jats:sup>2+<\/jats:sup>\n                    equivalent\/g in the FRAP assay. Pearson correlation analysis revealed strong and positive correlations between DPPH and TPC (r = 0.998,\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.05) and FRAP with TFC (r = 0.999,\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.05) and indicated a significant association between phenolic and flavonoid compounds and antioxidant activity. ABTS values were also strongly correlated to TPC (r = 0.957) and TFC (r = 0.977). These findings highlight\n                    <jats:italic>G. cyanocarpa<\/jats:italic>\n                    as a potential source of natural antioxidants and recommend further work to isolate active compounds and explore their therapeutic importance in conditions associated with oxidative stress.\n                  <\/jats:p>","DOI":"10.1155\/bmri\/4377026","type":"journal-article","created":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T10:47:06Z","timestamp":1787222826000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Antioxidant Profiling of\n                    <i>Glycosmis cyanocarpa<\/i>\n                    : In Vitro Assays and Pearson\u2019s Correlation Study"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0585-8500","authenticated-orcid":false,"given":"Sania","family":"Ashrafi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5230-5580","authenticated-orcid":false,"given":"Sadia Tasnim","family":"Mina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-6272-6666","authenticated-orcid":false,"given":"Raihana Haque","family":"Jebin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0690-1451","authenticated-orcid":false,"given":"Firoj","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,20]]},"reference":[{"key":"e_1_2_10_1_2","first-page":"208","article-title":"Drug Development From Natural Products: Exploiting Synergistic Effects","volume":"48","author":"Ulrich-Merzenich G.","year":"2010","journal-title":"Indian Journal of Experimental Biology"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.4c00581"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.3390\/biom13020194"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2021.112865"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1021\/np400856h"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.2174\/2210315508666180622121212"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28052207"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/10575639808048279"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27185972"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1021\/np9604238"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.3329\/bpj.v29i1.87383"},{"key":"e_1_2_10_12_2","first-page":"85","article-title":"Evaluation of In Vitro Antioxidant Potential of the Total Crude Alkaloid Extract of Glycosmis Pentaphylla (Retz.) Correa Leaves","volume":"8","author":"Prakasia P. P.","year":"2016","journal-title":"International Journal of Pharmacy and Pharmaceutical Sciences"},{"key":"e_1_2_10_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13205-026-04750-x"},{"key":"e_1_2_10_14_2","first-page":"137","article-title":"Antimicrobial, Antioxidant and Cytotoxic Effects of Methanolic Extracts of Leaves and Stems of Glycosmis Pentaphylla (Retz.)","volume":"1","author":"Howlader M. 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