{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T16:27:58Z","timestamp":1772987278680,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"vor","delay-in-days":301,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2025,1]]},"abstract":"\n Background and Objective<\/jats:title>\n Cameroon, located in Central Africa, is characterized by a high endemicity of hepatitis B. National studies estimate the prevalence of HBs antigen carriage to range between 8% and 15% in the general population. Identified high\u2010risk groups include adolescents and young adults, among whom university students represent a vulnerable population. The objective of this study was to assess the seroprevalence of hepatitis B viral biomarkers among students at the University of Yaound\u00e9 II in Cameroon.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n We conducted a cross\u2010sectional analytical study from February 20 to June 20, 2024. Samples were collected at the Soa campus of the University of Yaound\u00e9 II. Initial testing was performed using rapid diagnostic tests at the university, followed by ELISA (Fortress Diagnostics) at the blood bank of the Central Hospital of Yaound\u00e9. The detection of anti\u2010HBs, HBe antigen (HBeAg), anti\u2010HBe, and anti\u2010HBc was carried out using the Hightop HBV 5\u2010in\u20101 rapid test. Data were processed and analyzed using Microsoft Excel 2019 and SPSS Version 25. The chi\u2010square test, Fisher\u2019s exact test, and odds ratio calculations for comparing proportions and logistic regression were used to search for risk factors. The result was significant with a\n p<\/jats:italic>\n value less than 5%.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n A total of 250 students were tested. HBs antigen was positive in eight students (3.2%). Among these, anti\u2010HBs and HBeAg were absent, while anti\u2010HBe was positive in six out of eight (75.0%) and anti\u2010HBc was positive in all eight cases (100%). Only two students (0.8%) had been vaccinated against hepatitis B.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n All eight HBsAg\u2010positive students were in the chronic phase of hepatitis B infection. A history of blood transfusion and unprotected sexual intercourse was strongly associated with HBV infection. Vaccination coverage was extremely low, highlighting the need for targeted immunization programs in this population. Educational and awareness efforts regarding transmission routes and preventive measures must be strengthened.<\/jats:p>\n <\/jats:sec>","DOI":"10.1155\/bmri\/4866275","type":"journal-article","created":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T15:46:35Z","timestamp":1761752795000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Seroprevalence of Hepatitis B Virus Carriage Markers Among Students at the University of Yaound\u00e9 II, Cameroon"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-6564-2798","authenticated-orcid":false,"given":"Assiene Oyong Damase","family":"Serge","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1365-1844","authenticated-orcid":false,"given":"Minyemeck Marielle","family":"Flora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9408-6639","authenticated-orcid":false,"given":"Cedric","family":"Gueguim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Akono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dieudonn\u00e9","family":"Adiogo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,29]]},"reference":[{"key":"e_1_2_14_1_2","unstructured":"World Health Organization Hepatitis B Factsheet Available from:https:\/\/www.who.int\/fr\/news-room\/fact-sheets\/detail\/hepatitis-b. Accessed July 23 2025."},{"key":"e_1_2_14_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.revmed.2019.03.333"},{"key":"e_1_2_14_3_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a024935"},{"key":"e_1_2_14_4_2","doi-asserted-by":"publisher","DOI":"10.5281\/hsd.v19i3(S).1132"},{"key":"e_1_2_14_5_2","doi-asserted-by":"publisher","DOI":"10.5281\/hsd.v15i2.372"},{"key":"e_1_2_14_6_2","doi-asserted-by":"publisher","DOI":"10.1159\/000518618"},{"key":"e_1_2_14_7_2","doi-asserted-by":"publisher","DOI":"10.5281\/hsd.v25i6.5772"},{"key":"e_1_2_14_8_2","doi-asserted-by":"publisher","DOI":"10.4314\/ijbcs.v17i3.32"},{"key":"e_1_2_14_9_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0247267"},{"key":"e_1_2_14_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60207-5"},{"key":"e_1_2_14_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/v14091936"},{"key":"e_1_2_14_12_2","doi-asserted-by":"publisher","DOI":"10.5604\/16652681.1171756"},{"key":"e_1_2_14_13_2","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2022.41.61.32627"},{"key":"e_1_2_14_14_2","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2020.37.247.26070"},{"key":"e_1_2_14_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-015-1806-2"},{"key":"e_1_2_14_16_2","doi-asserted-by":"publisher","DOI":"10.5281\/hsd.v19i3(S).1122"},{"key":"e_1_2_14_17_2","doi-asserted-by":"publisher","DOI":"10.5281\/hsd.v22i11.3098"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/bmri\/4866275","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/bmri\/4866275","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/bmri\/4866275","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T10:55:13Z","timestamp":1772967313000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/bmri\/4866275"}},"subtitle":[],"editor":[{"given":"Hannah","family":"Wesley","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/bmri\/4866275"],"URL":"https:\/\/doi.org\/10.1155\/bmri\/4866275","archive":["Portico"],"relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2024-10-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"4866275"}}