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Current treatment modalities for DFU primarily include surgical debridement, negative\u2010pressure wound therapy, and anti\u2010infection measures. However, these approaches are limited by prolonged treatment duration, high costs, and suboptimal therapeutic outcomes. Adipose\u2010derived mesenchymal stem cells (ADMSCs) have garnered significant attention in wound repair and tissue regeneration due to their ability to secrete a variety of cytokines involved in the healing process. Exosomes, as key mediators of the paracrine effects underlying the therapeutic benefits of ADMSCs, are emerging as promising agents for wound repair. As a novel therapeutic strategy, exosomes have been increasingly investigated for the treatment of DFU. In this review, we summarize the applications and therapeutic potential of ADMSC\u2010exosomes in DFU, aiming to provide a valuable reference for its clinical management.<\/jats:p>","DOI":"10.1155\/bmri\/6652338","type":"journal-article","created":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T13:01:36Z","timestamp":1781182896000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Exosomes From Adipose\u2010Derived Mesenchymal Stem Cells: A New Prospective Therapy of Diabetic Foot 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