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However, the effects of MTSS on these muscles and tendons remain underexplored. This study is aimed at investigating changes in muscle and tendon volumes in this compartment, as well as cross\u2010sectional area measurements, using magnetic resonance imaging. Thirty individuals were divided into two groups: MTSS (<jats:italic>n<\/jats:italic> = 18; mean age 30.3 \u00b1 12.4) and control (<jats:italic>n<\/jats:italic> = 12; age 35.2 \u00b1 9.2). The anterior, deep posterior, superficial posterior, and lateral compartment muscles, along with their respective tendons, were compared between groups, and possible sex differences were also evaluated. The deep posterior compartment showed a significant volume difference of 0.41\u2009cm<jats:sup>3<\/jats:sup>\/kg<jats:sup>3<\/jats:sup>\/<jats:sup>4<\/jats:sup> in the MTSS group (<jats:italic>p<\/jats:italic> = 0.034), primarily due to the flexor hallucis longus (FHL), which had a 0.55\u2009cm<jats:sup>3<\/jats:sup>\/kg<jats:sup>3<\/jats:sup>\/<jats:sup>4<\/jats:sup> greater normalized volume (17.12% greater mean muscle volume) compared to controls (<jats:italic>p<\/jats:italic> = 0.023; Cohen <jats:italic>d<\/jats:italic> = 0.895). No association between sex and MTSS was found (<jats:italic>p<\/jats:italic> = 0.752). In conclusion, the FHL muscle exhibited increased normalized volume in the MTSS group compared to controls, with no sex\u2010related differences in MTSS. Clinicians should consider the assessment of FHL muscle volume in routine evaluations of patients presenting with symptoms suggestive of MTSS.<\/jats:p>","DOI":"10.1155\/bmri\/8827692","type":"journal-article","created":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T05:22:32Z","timestamp":1734326552000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["MRI\u2010Based Morphometric Comparison of Lower Leg Muscles and Tendons in Individuals With Medial Tibial Stress Syndrome"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3359-0786","authenticated-orcid":false,"given":"Lucas Nogueira","family":"de Oliveira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7511-5289","authenticated-orcid":false,"given":"Jo\u00e3o Luiz Quagliotti","family":"Durigan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline Ribeiro","family":"Sanchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrique","family":"Mansur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andressa Beatriz Beltr\u00e3o","family":"Rosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9126-3882","authenticated-orcid":false,"given":"Rita de C\u00e1ssia","family":"Marqueti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,12,16]]},"reference":[{"key":"e_1_2_12_1_2","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2015.5741"},{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17207457"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2014.03.008"},{"key":"e_1_2_12_4_2","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0b013e31818b98e6"},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2018.8062"},{"key":"e_1_2_12_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.36.2.95"},{"key":"e_1_2_12_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10140-016-1390-5"},{"key":"e_1_2_12_8_2","doi-asserted-by":"publisher","DOI":"10.2165\/00007256-200939070-00002"},{"key":"e_1_2_12_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.csm.2011.09.008"},{"key":"e_1_2_12_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/03635465010290060701"},{"key":"e_1_2_12_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546509343804"},{"key":"e_1_2_12_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/0095399703258776"},{"key":"e_1_2_12_13_2","doi-asserted-by":"publisher","DOI":"10.1177\/036354659502300418"},{"key":"e_1_2_12_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000126333.13806.87"},{"key":"e_1_2_12_15_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.183.3.1830635"},{"key":"e_1_2_12_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-2998(88)80003-5"},{"key":"e_1_2_12_17_2","first-page":"452","article-title":"Interpretation and classification of bone scintigraphic findings in stress fractures","volume":"28","author":"Zwas S. 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