{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T12:17:09Z","timestamp":1783081029081,"version":"3.54.6"},"reference-count":75,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"vor","delay-in-days":183,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Numerous recent studies have shown that long noncoding RNAs (lncRNAs) play a crucial role in the development of diverse cancers. Small nucleolar RNA host gene 18 (\n                    <jats:italic>SNHG18<\/jats:italic>\n                    ) is a cancer\u2010related lncRNA in the SNHG family, whose expression is dysregulated in various tumors and acts as either an oncogenic or tumor\u2010suppressive factor. Several studies have demonstrated that SNHG18 exhibits dual effects in various cancers. The role of this molecule is context\u2010dependent, acting as a tumor suppressor in certain cancers while exhibiting oncogenic properties in others. The expression of\n                    <jats:italic>SNHG18<\/jats:italic>\n                    is cancer\u2010type specific: it is upregulated in glioma, multiple myeloma, and lung cancer, but downregulated in bladder and hepatocellular cancer. Clinical studies have also found a correlation between\n                    <jats:italic>SNHG18<\/jats:italic>\n                    expression and prognosis in different cancers. We present an overview of studies on SNHG18, emphasizing its biological functions and its potential as a promising biomarker for the diagnosis and treatment of diverse cancer types.\n                  <\/jats:p>","DOI":"10.1155\/bmri\/9651227","type":"journal-article","created":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T11:26:18Z","timestamp":1783077978000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Oncogenic and Tumor\u2010Suppressive Roles of SNHG18: A Double\u2010Edged Long Noncoding RNA in Cancer"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4720-9575","authenticated-orcid":false,"given":"Vida","family":"Dehghani 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