{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T18:59:05Z","timestamp":1772996345961,"version":"3.50.1"},"reference-count":50,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,7,9]],"date-time":"2025-07-09T00:00:00Z","timestamp":1752019200000},"content-version":"vor","delay-in-days":189,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Behavioural Neurology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    Epilepsy\/seizures in meningioma patients may occur pre\u2010 or postoperatively, causing significant morbidity and impaired quality of life. Surgical excision is considered a standard management with variable rates of epilepsy\/seizure resolution reported after surgery. Employing a national database, we examined the pre\u2010 and postoperative incidences of epilepsy\/seizures and risk factors associated with postoperative epilepsy\/seizures in patients readmitted within 30 days and\/or 90 days following meningioma resection.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    The 2010\u20132014 Nationwide Readmissions Database was analyzed. Consecutive patients undergoing surgery for meningioma resection were identified using appropriate ICD\u20109\u2010CM codes. Standard descriptive techniques and multivariate regression were used to identify predictors of postoperative epilepsy\/seizure after discharge.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Among 46,107 patients undergoing meningioma resection at index hospitalization, 20.40% (\n                    <jats:italic>n<\/jats:italic>\n                    = 9408) had preoperative epilepsy\/seizure diagnosis. The mean patient age was 58.37 \u00b1 13.85\u2009years. Patients with preoperative epilepsy\/seizures were more likely to be male (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.001), frail (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.001), and with higher comorbidity index scores (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.001). The overall readmission rate was 30.36% and was higher among patients with preoperative epilepsy\/seizures (36.66% vs. 28.75%,\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.001). Respectively, 30\u2010 and 90\u2010day readmission rates were higher among patients (13.22% vs. 11.73%,\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.001) and (23.25% vs 20.30%,\n                    <jats:italic>p<\/jats:italic>\n                    = 0.04) with epilepsy\/seizure diagnosis at index admission. Predictors of postoperative epilepsy\/seizures at 30\u2010 and 90\u2010day readmissions included the preoperative epilepsy\/seizure, malignant meningioma, peritumoral cerebral edema, and higher comorbidity index scores, while male sex was significant only at 30\u2010day readmissions. Intraoperative electrocorticography was associated with a decreased likelihood of postoperative epilepsy\/seizures.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    Development of epilepsy\/seizures after meningioma resection is likely multifactorial. Identifying factors associated with postoperative epilepsy\/seizures after discharge is important in triaging and closer monitoring of at\u2010risk patients and for adapting management to help improve outcomes.\n                  <\/jats:p>","DOI":"10.1155\/bn\/5717503","type":"journal-article","created":{"date-parts":[[2025,7,9]],"date-time":"2025-07-09T12:49:22Z","timestamp":1752065362000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Predictors of Postoperative Epilepsy\/Seizures in Patients Readmitted After Meningioma Resection"],"prefix":"10.1155","volume":"2025","author":[{"given":"Rasha","family":"Elbadry","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony 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