{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T07:42:14Z","timestamp":1776066134612,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T00:00:00Z","timestamp":1775952000000},"content-version":"vor","delay-in-days":101,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002822","name":"Central South University","doi-asserted-by":"publisher","award":["YX202205"],"award-info":[{"award-number":["YX202205"]}],"id":[{"id":"10.13039\/501100002822","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82271503"],"award-info":[{"award-number":["82271503"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81801295"],"award-info":[{"award-number":["81801295"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC2503804"],"award-info":[{"award-number":["2022YFC2503804"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Behavioural Neurology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Temporal lobe epilepsy (TLE) is often accompanied by executive function (EF) impairment, highlighting the need for accessible and quantitative assessment approaches. In this study, we applied our previously developed game\u2010based executive function assessment tool (EFAT) to evaluate EF performance in TLE patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Thirty\u2010two TLE patients and 29 healthy controls (HCs) completed a comprehensive battery of standardized tests, including the Stroop Color\u2010Word Test (SCWT) and the Trail Making Test (TMT), as well as the EFAT. Metrics from the EFAT (number of touches, number of correct guesses, accuracy, and learning latency) were selected and analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Compared with HCs, TLE patients showed significant EF deficits, including longer completion times on TMT\u2010A (\n                      <jats:italic>t<\/jats:italic>\n                      (59) = 4.42,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001) and TMT\u2010B (\n                      <jats:italic>t<\/jats:italic>\n                      (59) = 3.50,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.001), as well as poorer SCWT\u20101 performance (\n                      <jats:italic>t<\/jats:italic>\n                      (59) = 2.22,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.036). In the EFAT, TLE patients exhibited more touches (\n                      <jats:italic>t<\/jats:italic>\n                      (59) = \u22122.75,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.008), fewer correct guesses (\n                      <jats:italic>t<\/jats:italic>\n                      (59) = \u22123.74,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001), and lower accuracy (\n                      <jats:italic>t<\/jats:italic>\n                      (59) = \u22122.65,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.010). Game\u2010derived metrics were significantly correlated with TMT scores.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>EFAT detected executive deficits in TLE patients across social and nonsocial conditions and offered an objective, engaging complementary tool for EF assessment. These findings support its preliminary clinical applicability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/bn\/6284292","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T06:47:16Z","timestamp":1776062836000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessing Executive Function in Patients With Temporal Lobe Epilepsy Through a Game\u2010Based Assessment Task"],"prefix":"10.1155","volume":"2026","author":[{"given":"Guang","family":"Yao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2082-3146","authenticated-orcid":false,"given":"Shirui","family":"Wen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Quanji","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3388-2575","authenticated-orcid":false,"given":"Yin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4426-3449","authenticated-orcid":false,"given":"Beibing","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7658-1399","authenticated-orcid":false,"given":"Li","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2776-1750","authenticated-orcid":false,"given":"Ding","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,4,12]]},"reference":[{"key":"e_1_2_12_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2018.01.024"},{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2018.04.022"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2022.08.010"},{"key":"e_1_2_12_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awac150"},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2022.976439"},{"key":"e_1_2_12_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2022.119665"},{"key":"e_1_2_12_7_2","doi-asserted-by":"publisher","DOI":"10.1684\/epd.2012.0483"},{"key":"e_1_2_12_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-012-6526-2"},{"key":"e_1_2_12_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2015.01.018"},{"key":"e_1_2_12_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2016.04.011"},{"key":"e_1_2_12_11_2","doi-asserted-by":"publisher","DOI":"10.2196\/games.9530"},{"key":"e_1_2_12_12_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2016.00209"},{"key":"e_1_2_12_13_2","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.6985"},{"key":"e_1_2_12_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/1087054716629711"},{"key":"e_1_2_12_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/arclin\/acw101"},{"key":"e_1_2_12_16_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2020.560021"},{"key":"e_1_2_12_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/pai.12690"},{"key":"e_1_2_12_18_2","doi-asserted-by":"publisher","DOI":"10.1080\/23279095.2021.1901101"},{"key":"e_1_2_12_19_2","volume-title":"The Corsini Encyclopedia of Psychology","author":"Allen D. 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