{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T14:18:40Z","timestamp":1783693120235,"version":"3.55.0"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:00:00Z","timestamp":1783641600000},"content-version":"vor","delay-in-days":190,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Canadian Respiratory Journal"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To analyze the distribution characteristics of pathogens in the bronchoalveolar lavage fluid of children with community\u2010acquired pneumonia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed the etiological data of 1526 children diagnosed and treated at the Maternal and Child Health Hospital of Hubei Province from January 1, 2023, to December 31, 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Pathogens were detected in 1524 of the 1526 children (99.9%). The five most frequently identified pathogens were\n                      <jats:italic>Mycoplasma pneumoniae<\/jats:italic>\n                      , rhinovirus, Epstein\u2012Barr virus,\n                      <jats:italic>Streptococcus pneumoniae<\/jats:italic>\n                      , and human bocavirus. The overall mixed infection rate was 62%. Epstein\u2012Barr virus, rhinovirus,\n                      <jats:italic>Streptococcus pneumoniae<\/jats:italic>\n                      , human bocavirus, and\n                      <jats:italic>Haemophilus influenzae<\/jats:italic>\n                      were the most common co\u2010infections of\n                      <jats:italic>Mycoplasma pneumoniae<\/jats:italic>\n                      .\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                      and\n                      <jats:italic>Pneumocystis jirovecii<\/jats:italic>\n                      infections were more common in males than in females. Human bocavirus, parainfluenza virus, respiratory syncytial virus,\n                      <jats:italic>Cytomegalovirus<\/jats:italic>\n                      ,\n                      <jats:italic>Pneumocystis jirovecii<\/jats:italic>\n                      , and WU polyomavirus were more prevalent in infants and young children, and Epstein\u2012Barr virus was more common in preschool\u2010aged and school\u2010aged children. More than half (51.6%) of the\n                      <jats:italic>Mycoplasma pneumoniae<\/jats:italic>\n                      infections occurred in autumn.\n                      <jats:italic>Mycobacterium tuberculosis complex<\/jats:italic>\n                      , human parainfluenza virus, and\n                      <jats:italic>Cytomegalovirus<\/jats:italic>\n                      were more common in spring and summer, and influenza B virus and adenovirus were more common in autumn and winter. Respiratory syncytial virus, influenza A virus, and\n                      <jats:italic>Fusobacterium nucleatum<\/jats:italic>\n                      were more common in winter and spring. Enteroviruses were more prevalent in summer and autumn.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The positive rate of pathogen detection in bronchoalveolar lavage fluid was extremely high. Most patients presented with mixed infections, and the distribution of some pathogens varied by sex, age, and season.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/carj\/8872950","type":"journal-article","created":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T14:00:26Z","timestamp":1783692026000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pathogen Profile of Pediatric Community\u2010Acquired Pneumonia in Wuhan, 2023: A BALF\u2010Based 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