{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T18:59:41Z","timestamp":1779217181722,"version":"3.51.4"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"vor","delay-in-days":113,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Ceftriaxone\u2010associated cholelithiasis is an uncommon but well\u2010recognized adverse effect in pediatric patients, resulting from precipitation of ceftriaxone\u2013calcium complexes within bile. Although often asymptomatic and transient, its radiologic appearance may mimic true gallstones and lead to unnecessary surgical intervention. We report a 2\u2010year\u2010old male child, born prematurely at 34\u2009weeks of gestation, who was incidentally diagnosed with gallbladder stones during follow\u2010up evaluation after multiple hospital admissions for dehydration and presumed infections treated with high\u2010dose intravenous ceftriaxone. The child was asymptomatic for biliary disease, with normal physical examination and laboratory findings. Abdominal ultrasonography demonstrated multiple mobile echogenic foci with posterior acoustic shadowing, the largest measuring 1.1\u2009cm, without evidence of inflammation or biliary obstruction. Given the absence of symptoms and identifiable hemolytic or metabolic disorders, conservative management with close follow\u2010up was adopted. Repeat ultrasonography after 12\u2009weeks showed complete spontaneous resolution of the gallstones. This case highlights the importance of recognizing ceftriaxone\u2010associated cholelithiasis in young children to help avoid unnecessary surgical intervention in appropriately selected asymptomatic patients through appropriate conservative management.<\/jats:p>","DOI":"10.1155\/carm\/6644319","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T13:31:58Z","timestamp":1777037518000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ceftriaxone\u2010Associated Cholelithiasis in a Premature Toddler From Ethiopia: A Case Report"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-6726-5757","authenticated-orcid":false,"given":"Kaleb Assefa","family":"Berhane","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selamawit","family":"Tesfaye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meron","family":"Zeleke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adu Dufera","family":"Moti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dawit Taye","family":"Endalew","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lela Alemayehu","family":"Gebeyehu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanuel Getu","family":"Gebreselassie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,4,24]]},"reference":[{"key":"e_1_2_13_1_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232113376"},{"key":"e_1_2_13_2_2","first-page":"588","article-title":"Cholelithiasis in Childhood: A Cohort Study in North of Iran","volume":"23","author":"Dooki M. R.","year":"2013","journal-title":"Iranian Journal of Pediatrics"},{"key":"e_1_2_13_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijso.2023.100705"},{"key":"e_1_2_13_4_2","doi-asserted-by":"crossref","unstructured":"MirzaS. N. Gall Stones in Pediatric Population [Internet]. Gallstones-Review and Recent Progress 2022 IntechOpen https:\/\/doi.org\/10.5772\/intechopen.99020.","DOI":"10.5772\/intechopen.99020"},{"key":"e_1_2_13_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.7620"},{"key":"e_1_2_13_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/omcr\/omae062"},{"key":"e_1_2_13_7_2","doi-asserted-by":"publisher","DOI":"10.3390\/jpm13040671"},{"key":"e_1_2_13_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s43066-020-00037-9"},{"key":"e_1_2_13_9_2","doi-asserted-by":"publisher","DOI":"10.33545\/26643685.2018.v1.i1a.7"},{"key":"e_1_2_13_10_2","doi-asserted-by":"publisher","DOI":"10.4314\/ejhs.v27i3.13"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/carm\/6644319","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/carm\/6644319","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/carm\/6644319","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T13:32:00Z","timestamp":1777037520000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/carm\/6644319"}},"subtitle":[],"editor":[{"given":"Simon Ching-Shun","family":"Kao","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/carm\/6644319"],"URL":"https:\/\/doi.org\/10.1155\/carm\/6644319","archive":["Portico"],"relation":{},"ISSN":["1687-9627","1687-9635"],"issn-type":[{"value":"1687-9627","type":"print"},{"value":"1687-9635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-07-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"6644319"}}