{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T22:29:30Z","timestamp":1773008970109,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T00:00:00Z","timestamp":1769472000000},"content-version":"vor","delay-in-days":26,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Appendiceal mucoceles (AMs) are rare pathological entities characterized by the accumulation of mucin within the appendiceal lumen. They may arise from either non\u2010neoplastic or neoplastic processes, including low\u2010grade appendiceal mucinous neoplasms (LAMNs). Due to their variable clinical presentation and often incidental discovery, diagnosis can be challenging. We report the case of a 29\u2010year\u2010old female who presented with a 3\u2010month history of constipation and intermittent abdominal pain. Physical examination revealed mild right lower quadrant tenderness without signs of peritonitis. Laboratory findings were unremarkable. Abdominal CT demonstrated a cystic, fluid\u2010filled structure at the base of the appendix. Colonoscopy revealed a glossy, dome\u2010shaped protrusion at the appendiceal orifice, consistent with a mucocele. The patient underwent an elective laparoscopic appendectomy. Histopathologic examination confirmed the diagnosis of LAMN. Her postoperative course was uneventful, and she remained asymptomatic on follow\u2010up. This case illustrates the diagnostic complexity of appendiceal mucoceles, particularly in young adults, where the condition is uncommon. The combination of cross\u2010sectional imaging and endoscopic evaluation was pivotal in establishing the diagnosis. Early surgical management was crucial to prevent rupture and the potential development of pseudomyxoma peritonei. Clinicians should maintain a high index of suspicion for AMs in patients with unexplained gastrointestinal symptoms and characteristic imaging findings. Prompt diagnosis and appropriate surgical intervention ensure favorable outcomes and prevent serious complications.<\/jats:p>","DOI":"10.1155\/carm\/7538312","type":"journal-article","created":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T10:31:52Z","timestamp":1769509912000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Low\u2010Grade Appendiceal Mucinous Neoplasm: A Case Highlighting Diagnostic and Management Considerations"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-2951-210X","authenticated-orcid":false,"given":"Ali","family":"Hamdan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8718-0711","authenticated-orcid":false,"given":"Jana","family":"Khalil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Razan Abou","family":"Zeid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-6998-6288","authenticated-orcid":false,"given":"Kelly Katherine","family":"Karam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8491-0790","authenticated-orcid":false,"given":"Philippe","family":"Attieh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1914-320X","authenticated-orcid":false,"given":"Karam","family":"Karam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1541-6009","authenticated-orcid":false,"given":"Lamia","family":"Azizi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3204-9098","authenticated-orcid":false,"given":"Elias","family":"Fiani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,27]]},"reference":[{"key":"e_1_2_12_1_2","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.890837"},{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.9738\/CC139.1"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2015.02.042"},{"key":"e_1_2_12_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000017149"},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v11.i30.4761"},{"key":"e_1_2_12_6_2","first-page":"565","article-title":"Appendiceal Mucocele-Case Report and Review of the Literature","volume":"110","author":"Asenov Y.","year":"2015","journal-title":"Chirurgia (Bucharest, Romania)"},{"key":"e_1_2_12_7_2","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2017-0081"},{"key":"e_1_2_12_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diii.2013.07.015"},{"key":"e_1_2_12_9_2","first-page":"788","article-title":"Appendiceal Mucocele: Clinical and Imaging Features of 14 Cases","volume":"109","author":"Malya F. U.","year":"2014","journal-title":"Chirurgia (Bucharest, Romania)"},{"key":"e_1_2_12_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12094-023-03356-6"},{"key":"e_1_2_12_11_2","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-020-08316-w"},{"key":"e_1_2_12_12_2","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13111827"},{"key":"e_1_2_12_13_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v19.i30.5021"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/carm\/7538312","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/carm\/7538312","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/carm\/7538312","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T20:38:02Z","timestamp":1773002282000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/carm\/7538312"}},"subtitle":[],"editor":[{"given":"Poulami","family":"Jha","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/carm\/7538312"],"URL":"https:\/\/doi.org\/10.1155\/carm\/7538312","archive":["Portico"],"relation":{},"ISSN":["1687-9627","1687-9635"],"issn-type":[{"value":"1687-9627","type":"print"},{"value":"1687-9635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-02-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"7538312"}}