{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T21:21:20Z","timestamp":1773523280999,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"vor","delay-in-days":48,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Since the declaration of the coronavirus disease 2019 (COVID\u201019) pandemic in late 2019, COVID\u201019 has remained a global concern. Elderly patients with hematological malignancies are immunocompromised and thus highly susceptible to COVID\u201019 infection and severe acute respiratory syndrome (SARS), posing significant clinical challenges. This report describes the diagnosis and treatment of a patient with multiple myeloma (MM) who developed SARS\u2010CoV\u20102 infection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We collected general patient information, clinical features, laboratory results, chest CT imaging, electronic bronchoscopy results, and clinical results for analysis. This case report was approved by the Institutional Review Committee of Baiyin First People\u2019s Hospital, and informed consent was obtained from the patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcomes<\/jats:title>\n                    <jats:p>We report a case of a 66\u2010year\u2010old male newly diagnosed with multiple myeloma who developed a SARS\u2010CoV\u20102 infection following chemotherapy. His clinical condition showed marked improvement after the initiation of nirmatrelvir\/ritonavir therapy. This case underscores the heightened susceptibility of immunocompromised patients to SARS\u2010CoV\u20102 and highlights the therapeutic importance of early administration of antiviral agents. A comprehensive understanding of the increased risk of opportunistic infections in patients with multiple myeloma postchemotherapy is essential for optimizing disease management and improving clinical outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Patients with MM have impaired immune function and are at high risk for severe infections during treatment. Proactive infection prevention and early intervention are essential to improving outcomes during treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/carm\/7967791","type":"journal-article","created":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T05:07:53Z","timestamp":1771477673000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Successful Treatment of Multiple Myeloma Complicated With SARS\u2010CoV\u20102 Infection: A Case Report"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6259-5068","authenticated-orcid":false,"given":"Yuna","family":"Meng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baoying","family":"Duan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lixian","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenjiao","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6124-0399","authenticated-orcid":false,"given":"Fang","family":"Wan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,18]]},"reference":[{"key":"e_1_2_8_1_2","doi-asserted-by":"publisher","DOI":"10.4103\/jdmimsu.jdmimsu_137_22"},{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.25122\/jml-2020-0184"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.56308"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-021-04594-w"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/03000605221082875"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.02037"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2020.105954"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(21)00278-7"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(20)30124-1"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2022.103623"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1182\/hematology.2022000334"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.22.01365"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1182\/hematology.2022000396"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2024.101218"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41408-020-00372-5"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-023-01920-1"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.3390\/v15102066"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2020001907"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/carm\/7967791","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/carm\/7967791","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/carm\/7967791","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T20:38:30Z","timestamp":1773002310000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/carm\/7967791"}},"subtitle":[],"editor":[{"given":"Poulami","family":"Jha","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/carm\/7967791"],"URL":"https:\/\/doi.org\/10.1155\/carm\/7967791","archive":["Portico"],"relation":{},"ISSN":["1687-9627","1687-9635"],"issn-type":[{"value":"1687-9627","type":"print"},{"value":"1687-9635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-03-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"7967791"}}