{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T13:35:19Z","timestamp":1780925719021,"version":"3.54.1"},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T00:00:00Z","timestamp":1763596800000},"content-version":"vor","delay-in-days":323,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    <jats:italic>Hafnia alvei<\/jats:italic>\n                    is a rare opportunistic pathogen of the Enterobacteriaceae family, typically regarded as a gastrointestinal commensal. However, it has been implicated in serious infections, particularly in immunocompromised patients, posing diagnostic and therapeutic challenges. We present the case of a 70\u2010year\u2010old woman with a history of cryptogenic cirrhosis postliver transplant, complicated by sepsis and advanced pancreatic adenocarcinoma under palliative care. She developed a urinary tract infection caused by\n                    <jats:italic>Hafnia alvei<\/jats:italic>\n                    and\n                    <jats:italic>Klebsiella oxytoca<\/jats:italic>\n                    , confirmed by cultures. Despite targeted antibiotic therapy with vancomycin and ciprofloxacin, her condition deteriorated, leading to death due to oncologic disease progression. This case underscores the pathogenic potential of\n                    <jats:italic>Hafnia alvei<\/jats:italic>\n                    , its role in polymicrobial infections, and the importance of antimicrobial susceptibility testing. Raising awareness of this under\u2010recognized pathogen is crucial to improving outcomes in vulnerable populations.\n                  <\/jats:p>","DOI":"10.1155\/carm\/8872086","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T19:18:42Z","timestamp":1763666322000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["<i>Hafnia alvei<\/i>\n                    Infections: Clinical Characteristics and Therapeutic Challenges of an Uncommon Pathogen"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7079-717X","authenticated-orcid":false,"given":"Jorge Eduardo","family":"Herrera Parra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc\u00eda","family":"Antu\u00f1a Montes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah Elisabeth","family":"Rodr\u00edguez Santiago","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Guti\u00e9rrez Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva Mar\u00eda","family":"L\u00f3pez \u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Burgos Bencosme","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,20]]},"reference":[{"key":"e_1_2_8_1_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.19.1.12-28.2006"},{"key":"e_1_2_8_2_2","article-title":"Rare Cause of Lung Tumour-Pulmonary Infection With Hafnia alvei: A Case Report","volume":"76","author":"Briegel I.","year":"2022","journal-title":"Pneumologie"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/1476-0711-5-12"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2004.10.008"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.6471"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2011.00600.x"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcr.2017.01.019"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2020-237061"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1086\/592704"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/carm\/8872086","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/carm\/8872086","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/carm\/8872086","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T17:57:41Z","timestamp":1773770261000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/carm\/8872086"}},"subtitle":[],"editor":[{"given":"Takanobu","family":"Hirosawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/carm\/8872086"],"URL":"https:\/\/doi.org\/10.1155\/carm\/8872086","archive":["Portico"],"relation":{},"ISSN":["1687-9627","1687-9635"],"issn-type":[{"value":"1687-9627","type":"print"},{"value":"1687-9635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2025-02-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"8872086"}}