{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T08:22:47Z","timestamp":1787386967705,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T00:00:00Z","timestamp":1787356800000},"content-version":"vor","delay-in-days":233,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovascular Therapeutics"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Primary percutaneous coronary intervention (pPCI) is the gold\u2010standard reperfusion strategy for acute ST\u2010elevation myocardial infarction (STEMI). However, the conventional two\u2010catheter percutaneous coronary intervention (C\u2010PCI) workflow requires sequential use of diagnostic and guiding catheters, causing avoidable procedural delays. Single\u2010catheter percutaneous coronary intervention (SC\u2010PCI) uses a single universal guiding catheter for both coronary angiography and intervention, improving intraprocedural efficiency, but comparative data remain limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single\u2010center retrospective cohort study enrolled 268 consecutive STEMI patients undergoing transradial pPCI. Using 1:1 propensity score matching (PSM), baseline confounders were balanced between the SC\u2010PCI and C\u2010PCI groups. The primary endpoint was puncture\u2010to\u2010balloon (P2B) time; secondary endpoints included core procedural time metrics, intraprocedural exposure, safety, and short\u2010term outcomes. Exploratory subgroup analyses were performed to assess the consistency of treatment effect.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After PSM, 120 well\u2010balanced patients (60 per group) were included. SC\u2010PCI significantly reduced P2B time (median 9.5 vs. 15.5\u2009min,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001), along with shorter puncture\u2010to\u2010angiography time, cath\u2010lab door\u2010to\u2010balloon time, fluoroscopy duration, and lower contrast volume (all\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.05). No statistically significant differences were observed in procedural success, overall complication rates, or in\u2010hospital mortality between groups. In exploratory subgroup analyses, the P2B benefit was consistent across subgroups, with no significant interactions (all\n                      <jats:italic>p<\/jats:italic>\n                      for interaction &gt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this propensity\u2010matched STEMI cohort, SC\u2010PCI was associated with shorter P2B time and improved intraprocedural efficiency, with no significant differences in periprocedural safety outcomes, suggesting that SC\u2010PCI may be a promising strategy to optimize STEMI interventional workflows.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/cdr\/4057540","type":"journal-article","created":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T07:26:58Z","timestamp":1787383618000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Single\u2010Catheter Versus Conventional Two\u2010Catheter Primary PCI in STEMI: A 1:1 Propensity Score\u2010Matched Cohort Study"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-6668-103X","authenticated-orcid":false,"given":"Xin","family":"Kou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5236-0767","authenticated-orcid":false,"given":"Sen","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9088-9442","authenticated-orcid":false,"given":"Hang","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0168-2238","authenticated-orcid":false,"given":"Lingyun","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,22]]},"reference":[{"key":"e_1_2_15_1_2","doi-asserted-by":"publisher","DOI":"10.14797\/mdcj-14-1-14"},{"key":"e_1_2_15_2_2","first-page":"e771","article-title":"2025 ACC\/AHA\/ACEP\/NAEMSP\/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes: A Report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"151","author":"Rao S. 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