{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T05:07:33Z","timestamp":1784264853676,"version":"3.55.0"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T00:00:00Z","timestamp":1784160000000},"content-version":"vor","delay-in-days":196,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005090","name":"Beijing Nova Program","doi-asserted-by":"publisher","award":["20220484222"],"award-info":[{"award-number":["20220484222"]}],"id":[{"id":"10.13039\/501100005090","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovascular Therapeutics"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Patients with three\u2010vessel coronary artery disease (3V\u2010CAD) remain at heterogeneous risk for major adverse cardiovascular and cerebrovascular events (MACCE) after revascularization. Magnetocardiography (MCG) is a noncontact and radiation\u2010free technique that may capture electrophysiological abnormalities not reflected by anatomical risk scores. This study evaluated the exploratory prognostic value of MCG\u2010derived parameters in patients with 3V\u2010CAD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single\u2010center prospective cohort study included 544 patients with 3V\u2010CAD who underwent coronary revascularization. MCG recordings were obtained before revascularization using a 36\u2010channel optically pumped magnetometer\u2010based system. The primary endpoint was MACCE, defined as cardiac death, stroke, myocardial infarction, or unplanned revascularization. Cox regression models were constructed using clinical variables, SYNTAX score, and an MCG composite variable. Model performance was assessed using discrimination, calibration, decision curve analysis, and bootstrap internal validation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      During a median follow\u2010up of 725 days, 37 patients (6.8%) experienced MACCE. The SYNTAX score was independently associated with MACCE after adjustment for clinical variables and MCG score (hazard ratio [HR], 1.08; 95% confidence interval [CI], 1.04\u20131.12;\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001). The MCG composite variable was also associated with MACCE after adjustment for clinical variables and SYNTAX score (HR, 2.74; 95% CI, 1.57\u20134.79;\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001). Model discrimination increased from 0.596 for clinical variables alone to 0.682 after adding SYNTAX score and to 0.727 after adding MCG. However, the improvement from the clinical\u2009+\u2009SYNTAX model to the MCG\u2010added model was not statistically significant (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.17). Bootstrap validation showed an optimism\u2010corrected\n                      <jats:italic>C<\/jats:italic>\n                      \u2010index of 0.672.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>MCG\u2010derived parameters were associated with MACCE and may provide complementary electrophysiological information for exploratory risk stratification in patients with 3V\u2010CAD after revascularization. Larger multicenter studies with external validation are needed to confirm its complementary prognostic value.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>Chinese Clinical Trial Registry identifier: ChiCTR2200066942<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/cdr\/5552371","type":"journal-article","created":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T04:55:50Z","timestamp":1784264150000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Magnetocardiography for Exploratory Risk Stratification in Patients With Three\u2010Vessel Coronary Artery Disease: A Single\u2010Center Prospective Cohort 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