{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T08:31:42Z","timestamp":1767688302577,"version":"3.48.0"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T00:00:00Z","timestamp":1767657600000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Canadian Journal of Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To preliminarily explore the feasibility and clinical implications of using gadoxetic acid disodium (Gd\u2010EOB\u2010DTPA)\u2010enhanced magnetic resonance imaging (MRI) for assessing the gallbladder ejection fraction (GBEF) in patients with cholecystolithiasis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective analysis encompassed 81 patients with gallstones who underwent Gd\u2010EOB\u2010DTPA\u2010enhanced MRI. Gallbladder volume was measured during fasting and at 1\u2009h after a lipid\u2010rich meal to calculate the GBEF. Two radiologists independently reviewed the images for GBEF, structural anomalies, and biliary patency.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The mean GBEF was 62.29%\u2009\u00b1\u200925.2%. Sixty patients demonstrated a GBEF\u2009&gt;\u200950%, while 21 had a GBEF\u2009\u2264\u200950%. The imaging also facilitated the identification of gallbladder malformations (41\/81) and abnormal pancreaticobiliary junctions (20\/81). Bile flow into the gallbladder via the cystic duct and into the duodenum was observed in 66 patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This exploratory study suggests that Gd\u2010EOB\u2010DTPA\u2010enhanced MRI is a feasible modality for simultaneous anatomical evaluation and functional assessment of the GBEF in cholecystolithiasis patients. It provides a comprehensive visualization of biliary dynamics. However, the findings are preliminary, and further validation against standard modalities with controlled study design is required to establish its accuracy and clinical utility.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/cjgh\/8851215","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T08:27:07Z","timestamp":1767688027000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Preliminary Exploratory Study on the Application of Gd\u2010EOB\u2010DTPA\u2010Enhanced MRI for Assessing Gallbladder Ejection Fraction in Cholecystolithiasis Patients"],"prefix":"10.1155","volume":"2026","author":[{"given":"Ruikun","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boqian","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaobing","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuan","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renjie","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingteng","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hengyu","family":"Tian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qinghua","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shenfeng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhujing","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7625-948X","authenticated-orcid":false,"given":"Hanqing","family":"Lyu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4401-7158","authenticated-orcid":false,"given":"Jialin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,6]]},"reference":[{"key":"e_1_2_14_1_2","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/9674565"},{"key":"e_1_2_14_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2017.09.003"},{"key":"e_1_2_14_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-013-2880-4"},{"key":"e_1_2_14_4_2","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.12.9332"},{"key":"e_1_2_14_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.suc.2014.01.004"},{"key":"e_1_2_14_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/RCT.0b013e31821f4e29"},{"key":"e_1_2_14_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.23816"},{"key":"e_1_2_14_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2016.04.009"},{"key":"e_1_2_14_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/ans.16003"},{"key":"e_1_2_14_10_2","doi-asserted-by":"publisher","DOI":"10.7863\/ultra.14.10033"},{"key":"e_1_2_14_11_2","doi-asserted-by":"publisher","DOI":"10.2174\/1568008054064940"},{"key":"e_1_2_14_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1590-8658(03)00087-2"},{"key":"e_1_2_14_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-024-08597-1"},{"key":"e_1_2_14_14_2","volume-title":"Physiology, Gallbladder","author":"Jones M. W.","year":"2023"},{"key":"e_1_2_14_15_2","first-page":"954","article-title":"Two Cases of Gallbladder Agenesis and Review of Literature","volume":"45","author":"Praseedom R.","year":"1998","journal-title":"Hepato-Gastroenterology"}],"container-title":["Canadian Journal of Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/cjgh\/8851215","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T08:27:09Z","timestamp":1767688029000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/cjgh\/8851215"}},"subtitle":[],"editor":[{"given":"Neetu","family":"Rawal","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/cjgh\/8851215"],"URL":"https:\/\/doi.org\/10.1155\/cjgh\/8851215","archive":["Portico"],"relation":{},"ISSN":["2291-2789","2291-2797"],"issn-type":[{"value":"2291-2789","type":"print"},{"value":"2291-2797","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2024-08-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"8851215"}}