{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:42:40Z","timestamp":1773013360922,"version":"3.50.1"},"reference-count":71,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T00:00:00Z","timestamp":1764028800000},"content-version":"vor","delay-in-days":328,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Canadian Journal of Infectious Diseases and Medical Microbiology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Chlamydia trachomatis<\/jats:italic>\n                      is the leading cause of sexually transmitted infections globally, responsible for various conditions including trachoma, genital infections, lymphogranuloma venereum, reactive arthritis, pneumonia, and neonatal conjunctivitis. This bacterium has 19 identified genotypes. This study aimed to evaluate the prevalence and genotype characterization of genital\n                      <jats:italic>Chlamydia<\/jats:italic>\n                      among women of reproductive age in both trachoma\u2010endemic and nonendemic regions of Tanzania.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      From May 2022 to May 2023, we conducted a cross\u2010sectional study involving 400 women attending antenatal and child health clinics in district hospitals located in trachoma\u2010endemic and nonendemic areas. Endocervical swabs were collected, and DNA was extracted for analysis. Polymerase chain reaction (PCR) was used to amplify the\n                      <jats:italic>ompA<\/jats:italic>\n                      gene, and the resulting PCR products were sequenced and compared with reference sequences from GenBank using BLAST to identify genotypes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The prevalence of genital\n                      <jats:italic>Chlamydia<\/jats:italic>\n                      was 2.3% (9 cases). The genotypes detected were L1 and F, each accounting for 11.1% of the cases. The infection rate was particularly high among women aged 25\u2009years or younger.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      The study found a significant prevalence of\n                      <jats:italic>Chlamydia trachomatis<\/jats:italic>\n                      among young women (\u2264\u200925\u2009years) and identified genotypes F and L1. These results highlight the need for ongoing surveillance and targeted public health strategies to manage and prevent\n                      <jats:italic>Chlamydia<\/jats:italic>\n                      infections, particularly among young women in both trachoma\u2010endemic and nonendemic regions of Tanzania.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/cjid\/5563047","type":"journal-article","created":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T11:12:33Z","timestamp":1764069153000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence and Genetic Characterization of\n                    <i>Chlamydia trachomatis<\/i>\n                    Isolates From Reproductive Age Women in Trachoma\u2010Endemic and Nonendemic Areas of Tanzania"],"prefix":"10.1155","volume":"2025","author":[{"given":"Rehesina H.","family":"Senkoro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6038-766X","authenticated-orcid":false,"given":"Donath","family":"Damian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hussein M.","family":"Juma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucy","family":"Namkinga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,25]]},"reference":[{"key":"e_1_2_12_1_2","volume-title":"Sexually Transmitted Infections (STIs) Key Fact Sheets","author":"WHO-World Health Organisation","year":"2023"},{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2018-053778"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-020-05664-6"},{"key":"e_1_2_12_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-022-00359-5"},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idcr.2021.e01367"},{"key":"e_1_2_12_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2017-053161"},{"key":"e_1_2_12_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ756"},{"key":"e_1_2_12_8_2","doi-asserted-by":"publisher","DOI":"10.4103\/idoj.idoj_410_19"},{"key":"e_1_2_12_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/apa.14227"},{"key":"e_1_2_12_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/0956462415618837"},{"key":"e_1_2_12_11_2","unstructured":"Tanzania Ministry of Health National Guidelines for Management of Sexually Transmitted and Reproductive Tract Infections Dodoma: Ministry of Health Community Development Gender Elderly and Children National AIDS Control Programme-NACP."},{"key":"e_1_2_12_12_2","doi-asserted-by":"publisher","DOI":"10.5603\/gp.a2018.0020"},{"key":"e_1_2_12_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-013-3122-3"},{"key":"e_1_2_12_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2021.09.020"},{"key":"e_1_2_12_15_2","doi-asserted-by":"publisher","DOI":"10.2217\/fmb.13.80"},{"key":"e_1_2_12_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-54886-5"},{"key":"e_1_2_12_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2013-051184.0597"},{"key":"e_1_2_12_18_2","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S57540"},{"key":"e_1_2_12_19_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2311.170758"},{"key":"e_1_2_12_20_2","doi-asserted-by":"crossref","unstructured":"De VriesH. 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