{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T18:16:09Z","timestamp":1772993769340,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,5,18]],"date-time":"2025-05-18T00:00:00Z","timestamp":1747526400000},"content-version":"vor","delay-in-days":137,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Critical Care"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    A man in his 40s with history of decompensated cirrhosis presented with acute leg pain. On presentation, he was febrile, tachycardic, and jaundiced. Laboratory findings included leukocytosis with bandemia, anemia, elevated creatinine, hyponatremia, lactic acidosis, hyperbilirubinemia, and elevated INR. His model for end\u2010stage liver disease\u2010sodium (MELD\u2010Na) score was 32. Diagnostic paracentesis did not suggest spontaneous bacterial peritonitis, but blood cultures revealed\n                    <jats:italic>Escherichia coli.<\/jats:italic>\n                    He received intravenous fluids, broad\u2010spectrum antibiotics, and packed RBC. He became acutely dyspneic, 1\u2009h into the transfusion. Over the next 36\u2009h, he developed worsening hypoxia with infiltrates on serial chest x\u2010rays despite adequate diuresis. He required intubation for respiratory failure and his hospital course was complicated by hepatic encephalopathy. Ultimately, he was discharged on hospital Day 18 and was retrospectively diagnosed with transfusion\u2010related acute lung injury (TRALI) Type II. This case focuses on management of TRALI in sepsis and highlights the elevated risk of transfusion\u2010associated reactions in liver failure patients and its mortality and morbidity.\n                  <\/jats:p>","DOI":"10.1155\/crcc\/7448355","type":"journal-article","created":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T02:38:37Z","timestamp":1747622317000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Recognition of Transfusion\u2010Related Acute Lung Injury in a Patient With End\u2010Stage Liver Disease and 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