{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T10:24:50Z","timestamp":1787826290731,"version":"build-2784847793"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:00:00Z","timestamp":1787788800000},"content-version":"vor","delay-in-days":238,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Critical Care"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Eclampsia is a rare but severe obstetric condition associated with maternal morbidity and mortality. Neurological complications are rare and often compounded by systemic involvement such as HELLP syndrome and coagulopathy. In this complex setting, multimodal neuromonitoring may support individualized management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case<\/jats:title>\n                    <jats:p>A 32\u2010year\u2010old woman at 37 weeks\u2032 gestation presented with new\u2010onset tonic\u2013clonic seizures, severe hypertension, and laboratory findings consistent with HELLP syndrome and disseminated intravascular coagulation. Following emergency cesarean section, brain CT revealed a right frontal intracranial hemorrhage (ICH) with mass effect. Given the high surgical risk related to coagulopathy, conservative management was pursued after placement of an invasive intracranial pressure (ICP) monitoring. In the neuro\u2013ICU, a multimodal monitoring strategy combining ICP waveform analysis, continuous electroencephalography, cerebral near\u2010infrared spectroscopy, and transcranial color\u2010coded duplex ultrasound (TCCD) guided therapy. Medical treatment successfully controlled intracranial hypertension and restored cerebral compliance. Daily TCCD examinations revealed progressively increased middle cerebral artery flow velocities, leading to early suspicion and radiological confirmation of reversible cerebral vasoconstriction syndrome (RCVS). Treatment with verapamil and levosimendan resulted in rapid normalization of Doppler velocities without systemic hypotension.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcome<\/jats:title>\n                    <jats:p>The patient showed progressive neurological recovery and was discharged to rehabilitation. After 6\u2009months, functional outcome was favorable (modified Rankin Scale\u2009=\u20092).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This case underscores the value of bedside TCCD integrated with multimodal neuromonitoring in the management of a complicated eclampsia with ICH and RCVS. Assessment of cerebral hemodynamics and perfusion may support safe conservative management in high\u2010risk neuro\u2010intensive care patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/crcc\/7731993","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T10:05:38Z","timestamp":1787825138000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multimodal Monitoring in Eclamptic Intracerebral Hemorrhage Complicated by Reversible Cerebral Vasoconstriction Syndrome (RCVS): A Case Report"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9456-439X","authenticated-orcid":false,"given":"Giada","family":"Cucciolini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0077-1790","authenticated-orcid":false,"given":"Marta","family":"Pillitteri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0032-8930","authenticated-orcid":false,"given":"Lara","family":"Vegnuti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6034-6044","authenticated-orcid":false,"given":"Francesco","family":"De Masi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9718-9943","authenticated-orcid":false,"given":"Baldassare","family":"Ferro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,27]]},"reference":[{"key":"e_1_2_15_1_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.14913"},{"key":"e_1_2_15_2_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.29080"},{"key":"e_1_2_15_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-025-05360-4"},{"key":"e_1_2_15_4_2","doi-asserted-by":"publisher","DOI":"10.1109\/EMBC46164.2021.9630516"},{"key":"e_1_2_15_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/s44158-023-00115-5"},{"key":"e_1_2_15_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-020-03105-z"},{"key":"e_1_2_15_7_2","doi-asserted-by":"crossref","DOI":"10.1017\/CBO9781107447905","volume-title":"Manual of Neurosonology","author":"Csiba L.","year":"2016"},{"key":"e_1_2_15_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2023.120853"},{"key":"e_1_2_15_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-022-03978-2"},{"key":"e_1_2_15_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-024-07756-2"},{"key":"e_1_2_15_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000003297"},{"key":"e_1_2_15_12_2","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/B978-0-323-93273-8.00007-9","volume-title":"Cottrell & Patel\u2032s Neuroanesthesia","author":"Matta B.","year":"2025"},{"key":"e_1_2_15_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000006345"},{"key":"e_1_2_15_14_2","volume-title":"Acta Neurochirurgica","author":"van der Harst J. 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