{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T22:17:21Z","timestamp":1777760241507,"version":"3.51.4"},"reference-count":8,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"vor","delay-in-days":118,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Critical Care"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The use of veno\u2010venous extracorporeal membrane oxygenation (VV\u2010ECMO) has risen exponentially since the COVID pandemic. VV\u2010ECMO has been utilized successfully to manage patients in status asthmaticus who have failed to respond adequately to conventional therapeutic interventions and mechanical ventilatory support. However, clear guidelines on the management of mechanical ventilation for these patients while on VV\u2010ECMO support appear to be lacking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>A 52\u2010year\u2010old male was placed on emergent VV\u2010ECMO for status asthmaticus after developing worsening hypercarbic respiratory failure despite mechanical ventilation and aggressive bronchodilator therapy. Once he was stabilized on VV\u2010ECMO, there was a dilemma in management priorities\u2014extubate the patient while keeping full VV\u2010ECMO support versus working to aggressively wean VV\u2010ECMO support while the patient is intubated. Ultimately, the decision was made to extubate the patient about 60\u2009h postcannulation. Postexubation, however, he was in respiratory distress with stridor and worsening bronchospasm and required maximum sweep on the VV\u2010ECMO in addition to increased respiratory support via noninvasive ventilation (NIV). Ultimately, he turned the corner, made progressive improvement, was weaned from VV\u2010ECMO support, and was decannulated 7 days after cannulation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Extubating a patient placed on VV\u2010ECMO for status asthmaticus is not a straightforward decision. One needs to consider the management priorities, anticipate the potential problems, and understand the implications of early extubation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/crcc\/7781487","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T13:53:16Z","timestamp":1777470796000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Successful Management of Status Asthmaticus via Veno\u2010Venous ECMO: Extubation Prior to Decannulation\u2014A Case Report"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9575-1960","authenticated-orcid":false,"given":"Sheryl S.","family":"Ang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,4,29]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.ss7005a1"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0b013e3181901ea5"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/0267659116670481"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.78672"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/nicc.12455"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000005673"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201109-1599OC"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10020251"}],"container-title":["Case Reports in Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crcc\/7781487","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crcc\/7781487","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crcc\/7781487","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T13:53:22Z","timestamp":1777470802000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crcc\/7781487"}},"subtitle":[],"editor":[{"given":"Lipi","family":"Buch","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/crcc\/7781487"],"URL":"https:\/\/doi.org\/10.1155\/crcc\/7781487","archive":["Portico"],"relation":{},"ISSN":["2090-6420","2090-6439"],"issn-type":[{"value":"2090-6420","type":"print"},{"value":"2090-6439","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-04-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"7781487"}}