{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T04:55:56Z","timestamp":1781326556343,"version":"3.54.1"},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T00:00:00Z","timestamp":1781222400000},"content-version":"vor","delay-in-days":162,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Infectious Diseases"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Nocardia<\/jats:italic>\n                      infection is an emerging concern in solid organ recipients due to prolonged immunosuppression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>\n                      We report the case of a 45\u2010year\u2010old woman with a history of cystic fibrosis who underwent bilateral lung transplantation. Eight years posttransplant, she developed progressive respiratory symptoms. Imaging revealed cavitary nodular lesions, and\n                      <jats:italic>Nocardia cyriacigeorgica<\/jats:italic>\n                      was isolated from bronchoalveolar lavage and sputum cultures. Treatment with meropenem and trimethoprim\u2010sulfamethoxazole led to clinical and radiological improvement.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      This case highlights the diagnostic challenges of\n                      <jats:italic>Nocardia<\/jats:italic>\n                      infections, the importance of microbiological interpretation, and the potential for late\u2010onset disease in transplant recipients despite prophylaxis. Awareness of\n                      <jats:italic>Nocardia<\/jats:italic>\n                      as an opportunistic pathogen is crucial for timely diagnosis and management. Our findings underscore the need for continued vigilance in solid organ transplant recipients, particularly in cases of persistent pulmonary infections and high immunosuppressive therapy.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/crdi\/2026205","type":"journal-article","created":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T04:05:51Z","timestamp":1781323551000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Breakthrough Pulmonary Nocardiosis Due to\n                    <i>Nocardia cyriacigeorgica<\/i>\n                    in a Lung Transplant Recipient in Brazil: A Case Report Highlighting Management Without Susceptibility Testing"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3370-7128","authenticated-orcid":false,"given":"Caian L.","family":"Vinhaes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Gabriela","family":"Gallegos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joana R.","family":"Deheinzelin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priscila","family":"Leon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6833-3811","authenticated-orcid":false,"given":"Bruno B.","family":"Andrade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3297-5948","authenticated-orcid":false,"given":"Silvia Vidal","family":"Campos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,12]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1097\/tp.0000000000004343"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/cmr.00027-21"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0002573"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1590\/s0036-46652007000400009"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2008.00338.x"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1053-2498(01)00394-1"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/tid.13478"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0090724"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2007.01078.x"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2023.10.008"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2008.00824.x"}],"container-title":["Case Reports in Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crdi\/2026205","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crdi\/2026205","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crdi\/2026205","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T04:05:53Z","timestamp":1781323553000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crdi\/2026205"}},"subtitle":[],"editor":[{"given":"Priya","family":"Gusain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/crdi\/2026205"],"URL":"https:\/\/doi.org\/10.1155\/crdi\/2026205","archive":["Portico"],"relation":{},"ISSN":["2090-6625","2090-6633"],"issn-type":[{"value":"2090-6625","type":"print"},{"value":"2090-6633","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2026-02-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2026205"}}