{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T07:48:25Z","timestamp":1782287305041,"version":"3.54.5"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T00:00:00Z","timestamp":1782259200000},"content-version":"vor","delay-in-days":174,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Infectious Diseases"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Lassa fever is a potentially fatal viral hemorrhagic disease caused by a ribonucleic acid (RNA) virus of the\n                      <jats:italic>Arenaviridae<\/jats:italic>\n                      family, endemic in West Africa. It is highly virulent and contagious in several countries, with a nonspecific clinical presentation that poses a major public health challenge. An in\u2010depth investigative survey was conducted in N\u2019Z\u00e9r\u00e9kor\u00e9 to identify the transmission chain of a confirmed case of Lassa fever.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>This study reports a confirmed case of Lassa fever diagnosed 13\u2009days after the onset of persistent fever. The disease was suspected at the regional hospital of N\u2019Z\u00e9r\u00e9kor\u00e9 following the worsening of the initial clinical picture, characterized by the onset of hemorrhagic manifestations and failure of antibiotic therapy. Confirmation of Lassa virus infection by reverse transcriptase\u2013polymerase chain reaction (RT\u2010PCR) on a blood sample was obtained a day prior to the patient\u2019s death. The patient did not receive ribavirin treatment and remained on the same antibiotic regimen (ceftriaxone) from the onset of fever, combined with dexamethasone, omeprazole, and a unit of blood transfusion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The therapeutic pathway of this confirmed Lassa fever case in N\u2019Z\u00e9r\u00e9kor\u00e9 highlights the need for improved management of viral hemorrhagic fevers and consideration of differential diagnoses when broad\u2010spectrum antibiotic therapy fails.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/crdi\/2672939","type":"journal-article","created":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T07:14:41Z","timestamp":1782285281000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Missed Opportunities for Timely Diagnosis and Effective Therapeutic Management of Prolonged Fever: A Case Study of Confirmed Lassa Fever in N\u2019Z\u00e9r\u00e9kor\u00e9, Guinea, 2022"],"prefix":"10.1155","volume":"2026","author":[{"given":"Ibrahima Sory","family":"Cherif","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0533-6518","authenticated-orcid":false,"given":"Esme Marie Laure","family":"Essis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamadou Alpha","family":"Diallo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loukou L\u00e9andre","family":"Konan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aly Antoine","family":"Kamano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Djoukou Olga Denise","family":"Kpebo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seydou","family":"Dia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamadou Oury","family":"Bald\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sory","family":"Cond\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatoumata","family":"Cherif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Momory","family":"Millimono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanta Mady","family":"Kouyat\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Loua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lila","family":"Cond\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,24]]},"reference":[{"key":"e_1_2_14_1_2","doi-asserted-by":"publisher","DOI":"10.5501\/wjv.v14.i3.108405"},{"key":"e_1_2_14_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep252801"},{"key":"e_1_2_14_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-4257-z"},{"key":"e_1_2_14_4_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0283643"},{"key":"e_1_2_14_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-025-11262-1"},{"key":"e_1_2_14_6_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0010289"},{"key":"e_1_2_14_7_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-019-6636-1"},{"key":"e_1_2_14_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2020.1796528"},{"key":"e_1_2_14_9_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.20-0487"},{"key":"e_1_2_14_10_2","first-page":"1","article-title":"Lassa Fever: a Clinical and Epidemiological Review","volume":"1","author":"Ogoina D.","year":"2013","journal-title":"Niger Delta Journal of Medicine and Medical Research"},{"key":"e_1_2_14_11_2","first-page":"707","article-title":"Diagnosis of Lassa Fever and the Isolation and Management of Patients","volume":"52","author":"Monath T. 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