{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T10:37:27Z","timestamp":1786617447626,"version":"build-2736575974"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"vor","delay-in-days":224,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Infectious Diseases"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    is one of the critical priority fungal pathogens as classified by the World Health Organization. Fluconazole resistance in\n                    <jats:italic>C. albicans<\/jats:italic>\n                    is increasingly being reported from different parts of the world. The epidemiology of antifungal resistance in Pakistan is evolving. While fluconazole resistance is rarely reported in invasive candidemia, it has been identified in noninvasive\n                    <jats:italic>Candida<\/jats:italic>\n                    isolates. Here, we describe the first case of candidemia with fluconazole\u2010resistant\n                    <jats:italic>C<\/jats:italic>\n                    .\n                    <jats:italic>albicans<\/jats:italic>\n                    with Y132H mutations in the\n                    <jats:italic>ERG11<\/jats:italic>\n                    gene from Pakistan. A 36\u2010year\u2010old male patient with comorbid conditions, including diabetes mellitus, hypertension, and a recent history of critical COVID\u201019 pneumonia, presented to the hospital emergency department with septic shock secondary to Fournier\u2019s gangrene. Blood culture confirmed fluconazole\u2010resistant\n                    <jats:italic>C. albicans<\/jats:italic>\n                    . Our case report underscores the urgent need for antifungal stewardship to prevent the escalating issue of antifungal resistance.\n                  <\/jats:p>","DOI":"10.1155\/crdi\/2911301","type":"journal-article","created":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T10:15:17Z","timestamp":1786616117000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["First Case of Candidemia With Fluconazole\u2010Resistant\n                    <i>Candida albicans<\/i>\n                    and Y132H Mutations in\n                    <i>ERG11<\/i>\n                    Gene From Pakistan"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1610-8748","authenticated-orcid":false,"given":"Nosheen","family":"Nasir","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9921-4660","authenticated-orcid":false,"given":"Joveria","family":"Farooqi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4982-2799","authenticated-orcid":false,"given":"Iffat","family":"Khanum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5024-1713","authenticated-orcid":false,"given":"Sadaf","family":"Zaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4585-2844","authenticated-orcid":false,"given":"Shariqa","family":"Batool","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9008-4556","authenticated-orcid":false,"given":"Najia","family":"Ghanchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2497-7847","authenticated-orcid":false,"given":"Kauser","family":"Jabeen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,13]]},"reference":[{"key":"e_1_2_13_1_2","article-title":"WHO Fungal Priority Pathogens List to Guide Research","author":"Organization W. 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