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Neonatal PF is a rarely reported but potentially disabling disorder associated with a high mortality rate and severe long\u2010term morbidity in survivors. We report an extremely low birth weight premature infant with PF associated with late\u2010onset Group B streptococcal sepsis. The infant survived but suffered a severe brain injury and autoamputation of all four extremities. We present this case and a review of the literature.<\/jats:p>","DOI":"10.1155\/crdi\/2925403","type":"journal-article","created":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T07:13:37Z","timestamp":1766474017000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Purpura Fulminans and Group B Streptococcal Sepsis in an Extremely Low Birth Weight Premature Infant"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7467-5874","authenticated-orcid":false,"given":"Surasak","family":"Puvabanditsin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8855-7684","authenticated-orcid":false,"given":"Aline","family":"Sandouk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5051-9722","authenticated-orcid":false,"given":"Ian","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0874-3373","authenticated-orcid":false,"given":"Mannan","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6791-121X","authenticated-orcid":false,"given":"Amrryn","family":"Halari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5995-9123","authenticated-orcid":false,"given":"Su Young","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3075-4498","authenticated-orcid":false,"given":"Rajeev","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,22]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1186\/1824-7288-35-10"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.3109\/08880018.2010.503339"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.889352"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1984.02140480017006"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/014107689108401022"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/fetalneonatal-2011-300907"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1002683"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1376186"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196706082762304"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/20499361221142732"},{"key":"e_1_2_9_11_2","first-page":"144","article-title":"Purpura Fulminans in Three Cases of Early-Onset Neonatal Group B Streptococcal Meningitis","volume":"11","author":"Lynn N. 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