{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:56:50Z","timestamp":1787504210216,"version":"build-2736575974"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T00:00:00Z","timestamp":1741910400000},"content-version":"vor","delay-in-days":72,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Infectious Diseases"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    Pregnancy induces physiological decline in maternal immunity. Ebola virus disease (EVD) in pregnancy is associated with obstetrical complications, and vaccination in early pregnancy is recommended, but may not be without risk.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Case Presentation:<\/jats:bold>\n                    We described neonatal survival after spontaneous maternal EVD recovery. This neonate was born to a 25\u2010year\u2010old mother admitted to an Ebola Treatment Unit (ETU) in July, 2020, after 11\u2009days of symptoms. She was vaccinated with rVSV\u2010ZEBOV three days before symptom onset and her real\u2010time polymerase chain of reaction (RT\u2010PCR) results confirmed EVD and malarial infection two days after, but she refused hospitalization. She was treated at home with PO ASAQ, amoxicillin, paracetamol, albendazole, omeprazole, and papaverine. Eleven days later, due to clinical deterioration and onset of vaginal hemorrhage, she finally accepted to be transferred in ETU. She was Parity 2, fetal age at admission was 5\u2009weeks and 3\u2009days. Upon admission, her EVD PCR measured NP 26.3 and GP 32.9. She did not receive monoclonal therapy against Ebola infection due to stock shortage. She received intravenous, artesunate, ceftriaxone, and papaverine. She experienced spontaneous resolution of EVD 18\u2009days after symptom onset and was discharged. At 40\u2009weeks gestation, seven and a half months after EVD recovery, she delivered a healthy female infant, APGAR 10\/10\/10, weighing 3450\u2009g. Maternal blood, adnexal, and newborn blood samples were RT\u2010PCR negative, and the mother and the baby were discharged after 14\u2009days. At our last follow\u2010up, in June 2023 (2\u2009years, 3\u2009months after delivery), the mother and the baby were in good health.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    Neonatal survival following spontaneous maternal recovery from EVD in the first trimester of gestation is rare but possible, even in the context of limited clinical resources for treatment.\n                  <\/jats:p>","DOI":"10.1155\/crdi\/2987569","type":"journal-article","created":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T08:20:26Z","timestamp":1741940426000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Neonatal Survival Following Spontaneous Maternal Recovery From Ebola Virus Disease in a Resource\u2010Limited Setting in Western Democratic Republic of the Congo"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3507-8388","authenticated-orcid":false,"given":"Prince","family":"Imani-Musimwa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0074-7538","authenticated-orcid":false,"given":"Emilie","family":"Grant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6836-8704","authenticated-orcid":false,"given":"Daniel","family":"Mukadi-Bamuleka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3266-0252","authenticated-orcid":false,"given":"Rigo","family":"Fraterne-Muhayangabo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Kitenge-Omasumbu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1556-3570","authenticated-orcid":false,"given":"Placide","family":"Mbala-Kingebeni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zacharie","family":"Tsongo-Kibendelwa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6511-0890","authenticated-orcid":false,"given":"Olivier","family":"Nyakio-Ngeleza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8165-2654","authenticated-orcid":false,"given":"Ines","family":"Claris-Mwatsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juakali","family":"Sihali-Kyolov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Th\u00e9ophile","family":"Barhwamire-Kabesha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4228-1968","authenticated-orcid":false,"given":"Celine","family":"Kavira-Malengera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-9950-0870","authenticated-orcid":false,"given":"Micheline","family":"Feza-Malira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6409-6299","authenticated-orcid":false,"given":"Richard","family":"Bitwe-Mihanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7197-8159","authenticated-orcid":false,"given":"Dieudonn\u00e9","family":"Sengeyi-Mushengezi-Amani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7182-2998","authenticated-orcid":false,"given":"Mija","family":"Ververs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,14]]},"reference":[{"key":"e_1_2_12_1_2","volume-title":"Case Fatality Rate for Ebola Disease, 1976\u20132022: A Meta-Analysis of Global Data","author":"Izudi J.","year":"2024"},{"key":"e_1_2_12_2_2","unstructured":"World Health Organization-WHO Ebola Virus Disease https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/ebola-virus-disease."},{"key":"e_1_2_12_3_2","unstructured":"US Centers for Disease Control and Prevention Ebola Disease Outbreaks by Species and Size Since 1976 2024 https:\/\/www.cdc.gov\/ebola\/outbreaks\/index.html."},{"key":"e_1_2_12_4_2","unstructured":"World Health Organization Democratic Republic of Congo. Rapport Technique: Revue apr\u00e9s action de la riposte aux 9e 10e 11e et 12e \u00e9pid\u00e9mies de maladie \u00e0 virus Ebola 2021."},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40249-017-0346-7"},{"key":"e_1_2_12_6_2","unstructured":"World Health Organization-WHO Guidelines for the Management of Pregnant and Breastfeeding Women in the Context of Ebola Virus Disease 2024 https:\/\/www.who.int\/publications\/i\/item\/978924000138."},{"key":"e_1_2_12_7_2","volume-title":"Pregnancy and Breastfeeding in the Context of Ebola: A Systematic Review","author":"Foeller M. 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