{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T09:56:11Z","timestamp":1791194171931,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:00:00Z","timestamp":1791158400000},"content-version":"vor","delay-in-days":277,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Infectious Diseases"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Splenic abscess is a rare but potentially life\u2010threatening condition, most frequently seen in immunocompromised individuals or those with significant underlying comorbidities. Monomicrobial bacterial infections predominate, whereas fungal or mixed infections are uncommon, particularly in immunocompetent hosts. Concurrent bacterial and fungal infection of the spleen is exceedingly rare. We report the case of a 30\u2010year\u2010old immunocompetent Indian male who presented with high\u2010grade fever, left upper quadrant abdominal pain, and gastrointestinal symptoms. Imaging demonstrated a multiseptated cystic lesion in the upper pole of the spleen consistent with abscess formation. Endoscopic ultrasound\u2010guided fine\u2010needle aspiration yielded purulent material, and culture revealed dual infection with\n                    <jats:italic>Salmonella enterica<\/jats:italic>\n                    serovar Paratyphi A and\n                    <jats:italic>Candida tropicalis<\/jats:italic>\n                    . Blood cultures and tuberculosis workup were negative. Despite broad\u2010spectrum empirical antimicrobial therapy, radiological progression necessitated laparoscopic drainage and debridement, followed by culture\u2010directed antibacterial therapy for a total of 5\u2009weeks and antifungal therapy for 6\u2009weeks. The patient achieved complete clinical and radiological resolution with preservation of splenic function. This case highlights the importance of maintaining a high index of clinical suspicion for splenic abscess and considering polymicrobial infection, including fungal pathogens, even in immunocompetent patients. Prompt microbiological diagnosis, early multidisciplinary involvement, timely spleen\u2010sparing source control, and targeted antimicrobial therapy guided by susceptibility testing facilitated successful organ preservation while avoiding splenectomy, ultimately resulting in a favorable clinical outcome.\n                  <\/jats:p>","DOI":"10.1155\/crdi\/3533752","type":"journal-article","created":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T09:43:38Z","timestamp":1791193418000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["An Unusual Bacterial\u2010Fungal Splenic Abscess in an Immunocompetent Host:\n                    <i>Salmonella Paratyphi A<\/i>\n                    and\n                    <i>Candida tropicalis<\/i>\n                    Co\u2010Infection"],"prefix":"10.1155","volume":"2026","author":[{"given":"Kapil","family":"Chahal","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases Fortis Memorial Research Institute &amp; Hospital  Gurugram India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0063-3444","authenticated-orcid":false,"given":"Neha","family":"Rastogi","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Fortis Memorial Research Institute &amp; Hospital  Gurugram India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3783-8846","authenticated-orcid":false,"given":"Swati","family":"Bhayana","sequence":"additional","affiliation":[{"name":"Department of Haematology, Paediatric Oncology Fortis Memorial Research Institute &amp; Hospital  Gurugram India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Javed","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatobiliary Sciences Fortis Memorial Research Institute &amp; Hospital  Gurugram India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rinkesh Kumar","family":"Bansal","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatobiliary Sciences Fortis Memorial Research Institute &amp; Hospital  Gurugram India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zubin Dev","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatobiliary Sciences Fortis Memorial Research Institute &amp; Hospital  Gurugram India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3927-0502","authenticated-orcid":false,"given":"Saurabh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology Fortis Memorial Research Institute &amp; Hospital  Gurugram India  jsd.js.cn"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narola","family":"Yanger","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatobiliary Sciences Fortis Memorial Research Institute &amp; Hospital  Gurugram India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neha","family":"Lal","sequence":"additional","affiliation":[{"name":"Department of Microbiology Fortis Memorial Research Institute &amp; Hospital  Gurugram India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6006-6309","authenticated-orcid":false,"given":"Shrinidhi","family":"Nathany","sequence":"additional","affiliation":[{"name":"Department of Haematology Fortis Memorial Research Institute &amp; Hospital  Gurugram India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikas","family":"Dua","sequence":"additional","affiliation":[{"name":"Department of Haematology, Paediatric Oncology Fortis Memorial Research Institute &amp; Hospital  Gurugram India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5769-8073","authenticated-orcid":false,"given":"Rahul","family":"Bhargava","sequence":"additional","affiliation":[{"name":"Department of Haematology Fortis Memorial Research Institute &amp; Hospital  Gurugram India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,5]]},"reference":[{"key":"e_1_2_12_1_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.73502"},{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.53042"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofac085"},{"key":"e_1_2_12_4_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.89325"},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.18771"},{"key":"e_1_2_12_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsha.2015.02.001"},{"key":"e_1_2_12_7_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v12.i3.460"},{"key":"e_1_2_12_8_2","doi-asserted-by":"publisher","DOI":"10.7812\/tpp\/16-139"},{"key":"e_1_2_12_9_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.65607"},{"key":"e_1_2_12_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-023-04626-5"},{"key":"e_1_2_12_11_2","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/8610657"},{"key":"e_1_2_12_12_2","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2011.52.2.288"},{"key":"e_1_2_12_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/ans.19178"},{"key":"e_1_2_12_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0377-1237(06)80167-x"},{"key":"e_1_2_12_15_2","article-title":"Typhoid Splenic Abscess: A Case Report and Literature Review","volume":"6","author":"Khan F. Y.","year":"2019","journal-title":"International Journal of Infection"},{"key":"e_1_2_12_16_2","doi-asserted-by":"publisher","DOI":"10.7883\/yoken.jjid.2020.518"}],"container-title":["Case Reports in Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crdi\/3533752","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crdi\/3533752","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crdi\/3533752","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T09:43:39Z","timestamp":1791193419000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crdi\/3533752"}},"subtitle":[],"editor":[{"given":"Priya","family":"Gusain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/crdi\/3533752"],"URL":"https:\/\/doi.org\/10.1155\/crdi\/3533752","archive":["Portico"],"relation":{},"ISSN":["2090-6625","2090-6633"],"issn-type":[{"value":"2090-6625","type":"print"},{"value":"2090-6633","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2026-04-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"3533752"}}