{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T12:13:23Z","timestamp":1788351203781,"version":"build-2803163510"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000},"content-version":"vor","delay-in-days":244,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Infectious Diseases"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      Sepsis secondary to crusted scabies is a rare but life\u2010threatening complication of\n                      <jats:italic>Sarcoptes scabiei<\/jats:italic>\n                      infestation, particularly in vulnerable and underserved populations. Misdiagnosis with other dermatological conditions may lead to inappropriate treatment and severe outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Findings<\/jats:title>\n                    <jats:p>A 50\u2010year\u2010old Indigenous man from the Brazilian Amazon presented with a one\u2010year history of generalized pruritus, diffuse hyperkeratotic and crusted skin lesions, and progressive clinical deterioration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Diagnosis, Interventions, and Outcomes<\/jats:title>\n                    <jats:p>\n                      The patient was initially misdiagnosed with Hansen\u2019s disease and atopic dermatitis and received prolonged corticosteroid therapy, which exacerbated his condition. Skin scraping confirmed crusted scabies, and blood cultures grew\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                      , establishing the diagnosis of sepsis secondary to skin infection. He was treated with oral ivermectin, topical 5% permethrin, and systemic antibiotics, with gradual tapering and discontinuation of corticosteroids. The patient achieved complete clinical recovery.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion (Take\u2010Home Message)<\/jats:title>\n                    <jats:p>This case highlights the critical importance of early recognition of crusted scabies and the risks associated with misdiagnosis and inappropriate immunosuppressive therapy. Prompt diagnosis and treatment are essential to prevent severe complications such as sepsis, particularly in resource\u2010limited and endemic settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/crdi\/5279255","type":"journal-article","created":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T11:19:06Z","timestamp":1788347946000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sepsis Secondary to Crusted Scabies Following Iatrogenic Treatment for Hansen\u2019s Disease in an Indigenous Amazonian Patient: A Case Report"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-3405-1707","authenticated-orcid":false,"given":"Ana Beatriz Nardelli da","family":"Silva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6799-3225","authenticated-orcid":false,"given":"Mait\u00ea Silva Martins","family":"Gadelha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5951-3308","authenticated-orcid":false,"given":"Giovanna Louren\u00e7o","family":"Cei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4405-3529","authenticated-orcid":false,"given":"Adriani Ferreira do","family":"Carmo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6481-0509","authenticated-orcid":false,"given":"Arlisson Macedo","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,2]]},"reference":[{"key":"e_1_2_13_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmaid.2025.102878"},{"key":"e_1_2_13_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-025-06856-y"},{"key":"e_1_2_13_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.19511"},{"key":"e_1_2_13_4_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182025000113"},{"key":"e_1_2_13_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2024.107036"},{"key":"e_1_2_13_6_2","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/9542857"},{"key":"e_1_2_13_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.9325"},{"key":"e_1_2_13_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/pde.154053"},{"key":"e_1_2_13_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.abd.2025.501127"},{"key":"e_1_2_13_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2009.02412.x"},{"key":"e_1_2_13_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.17602"},{"key":"e_1_2_13_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idcr.2026.e02577"}],"container-title":["Case Reports in Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crdi\/5279255","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crdi\/5279255","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crdi\/5279255","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T11:19:06Z","timestamp":1788347946000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crdi\/5279255"}},"subtitle":[],"editor":[{"given":"Priya","family":"Gusain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/crdi\/5279255"],"URL":"https:\/\/doi.org\/10.1155\/crdi\/5279255","archive":["Portico"],"relation":{},"ISSN":["2090-6625","2090-6633"],"issn-type":[{"value":"2090-6625","type":"print"},{"value":"2090-6633","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2026-04-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"5279255"}}