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Despite drug discontinuation and supportive measures, thrombocytopenia persisted, leading to the patient\u2019s death. This case highlights the complexities of drug\u2010induced immune thrombocytopenia in immunocompromised patients and emphasizes the risks associated with trimethoprim\u2013sulfamethoxazole.<\/jats:p>","DOI":"10.1155\/crdi\/5522047","type":"journal-article","created":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T09:52:20Z","timestamp":1770112340000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Drug\u2010Induced Immune Thrombocytopenia Secondary to Trimethoprim\u2013Sulfamethoxazole"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-3896-4189","authenticated-orcid":false,"given":"Christopher","family":"Cimperman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elysha","family":"Whitesel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy","family":"Ray","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina-Naeger","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Atyia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ismini","family":"Kourouni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corrilynn","family":"Hileman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,3]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2009.03360.x"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.21307\/immunohematology-2019-099"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2006.01787.x"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/940271"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2021.02.118"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.v82.9.2714.2714"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/aac.46.8.2723-2726.2002"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-08-302984"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.v79.4.942.bloodjournal794942"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/nejmra1009433"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.13469"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.14309\/01.ajg.0000963140.38497.48"}],"container-title":["Case Reports in Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crdi\/5522047","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crdi\/5522047","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crdi\/5522047","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T10:50:45Z","timestamp":1770720645000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crdi\/5522047"}},"subtitle":[],"editor":[{"given":"Piyush","family":"Baindara","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/crdi\/5522047"],"URL":"https:\/\/doi.org\/10.1155\/crdi\/5522047","archive":["Portico"],"relation":{},"ISSN":["2090-6625","2090-6633"],"issn-type":[{"value":"2090-6625","type":"print"},{"value":"2090-6633","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-03-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"5522047"}}