{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:55:55Z","timestamp":1790812555660,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:00:00Z","timestamp":1761177600000},"content-version":"vor","delay-in-days":295,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Infectious Diseases"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    <jats:italic>Candida blankii<\/jats:italic>\n                    has recently emerged as a pathogen of clinical significance, particularly in cases of candidemia. Here, we present two cases involving adult patients with complex medical histories. In one case,\n                    <jats:italic>C. blankii<\/jats:italic>\n                    was considered clinically significant, while in the other, it was regarded as a colonizer. The first case involves an 85\u2010year\u2010old male with multiple comorbidities, including chronic obstructive pulmonary disease and heart failure, who presented with a pleural effusion. Blood cultures revealed yeast which could not be identified by matrix\u2010assisted laser desorption\/ionization time\u2010of\u2010flight mass spectrometry (MALDI\u2010TOF MS), which was later identified as\n                    <jats:italic>C. blankii<\/jats:italic>\n                    after being sent to the provincial reference laboratory. The isolate showed high minimum inhibitory concentrations (MICs) to azoles. The second case involves a 60\u2010year\u2010old male with cirrhosis and multifocal pneumonia.\n                    <jats:italic>C. blankii<\/jats:italic>\n                    was isolated from bronchoalveolar lavage samples, though it was ultimately considered a colonizer rather than a pathogen in this instance. Initial identification via MALDI\u2010TOF MS was inconclusive, necessitating further molecular sequencing. The pathogen exhibited high MICs to azoles and lower MICs to echinocandins and polyenes. Both cases highlight the challenges in identifying\n                    <jats:italic>C. blankii<\/jats:italic>\n                    using conventional laboratory methods. Given the increasing reports of\n                    <jats:italic>C. blankii<\/jats:italic>\n                    as a pathogen, particularly in immunocompromised patients, our findings emphasize the need for heightened awareness and improved diagnostic techniques. Accurate and timely identification is crucial for appropriate therapeutic management, given the organism\u2019s unique susceptibility profile. Further research is necessary to understand the epidemiology, pathogenesis, and optimal treatment strategies for\n                    <jats:italic>C. blankii<\/jats:italic>\n                    infections.\n                  <\/jats:p>","DOI":"10.1155\/crdi\/5543654","type":"journal-article","created":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T11:34:30Z","timestamp":1761219270000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["<i>Candida blankii<\/i>\n                    : The Difficult Capture of a Fungus With Pathogenic Potential"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-8198-0658","authenticated-orcid":false,"given":"Ethan","family":"Smillie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arjun","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8882-1756","authenticated-orcid":false,"given":"Johan","family":"Delport","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2246-3471","authenticated-orcid":false,"given":"Ana","family":"Cabrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2410-6788","authenticated-orcid":false,"given":"Mohammedreza Rahimi","family":"Shahmirzadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3978-1823","authenticated-orcid":false,"given":"Fatimah","family":"AlMutawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,23]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1007\/bf02050372"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00029-06"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa193"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.ss7404a1"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-023-08050-0"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.3138\/jammi.3.1.04"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-024-02229-6"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2020.01.001"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmni.2018.06.008"},{"key":"e_1_2_11_10_2","article-title":"Candida blankii: New Agent in Cystic Fibrosis Airways?","volume":"15","author":"Zaragoza S.","year":"2018","journal-title":"Journal of Cystic Fibrosis"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41426-017-0015-8"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.14945"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.3390\/jof8020166"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mmcr.2024.100682"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro732"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/femspd\/ftx029"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02434889"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01397-19"},{"key":"e_1_2_11_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/aob\/mcp026"}],"container-title":["Case Reports in Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crdi\/5543654","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crdi\/5543654","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crdi\/5543654","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T17:55:22Z","timestamp":1773770122000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crdi\/5543654"}},"subtitle":[],"editor":[{"given":"Rajib","family":"Chowdhury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/crdi\/5543654"],"URL":"https:\/\/doi.org\/10.1155\/crdi\/5543654","archive":["Portico"],"relation":{},"ISSN":["2090-6625","2090-6633"],"issn-type":[{"value":"2090-6625","type":"print"},{"value":"2090-6633","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2024-08-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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