{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T19:13:17Z","timestamp":1770750797222,"version":"3.50.0"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T00:00:00Z","timestamp":1769817600000},"content-version":"vor","delay-in-days":30,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Infectious Diseases"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Malaria\u2010associated acute kidney injury (MAKI) is a formidable and potentially fatal complication of malaria. Early recognition and timely management can significantly reduce morbidity and mortality, particularly in resource\u2010limited settings. This case series describes five patients with imported\n                    <jats:italic>Plasmodium falciparum<\/jats:italic>\n                    complicated by MAKI who were treated at Kilimanjaro Christian Medical Center (KCMC) in northeastern Tanzania between December 2023 and January 2024. The cohort comprised of four males and one female, with a mean age of 38.2\u2009\u00b1\u200918.6\u2009years. All patients presented with a history of fever and a recent history of travel to high\u2010endemic regions. The mean serum creatinine and urea levels at admission were 736\u2009\u00b1\u2009346.4\u2009\u03bcmol\/L and 23.1\u2009\u00b1\u200914.1\u2009mmol\/L, respectively. Four patients required hemodialysis, and one experienced malaria recrudescence. Overall survival was 100%. This case series highlights pathophysiological mechanisms, clinical presentations, diagnostic challenges, and management outcomes of MAKI, illustrating its modified natural history. Despite advances in understanding MAKI, early diagnostic and treatment challenges persist. This case series aimed to elucidate the underrecognized burden and patterns of MAKI in a resource\u2010limited, low\u2010endemic region within an endemic country.\n                  <\/jats:p>","DOI":"10.1155\/crdi\/5583026","type":"journal-article","created":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T15:57:22Z","timestamp":1769875042000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Malaria\u2010Associated Acute Kidney Injury in a Low\u2010Endemic Region: A Case Series of Five Imported\n                    <i>Plasmodium falciparum<\/i>\n                    Infections"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-7763-9346","authenticated-orcid":false,"given":"Daniel P.","family":"Mujuni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7812-8042","authenticated-orcid":false,"given":"Abid M.","family":"Sadiq","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisha","family":"Luhwago","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Datius","family":"Mutalemwa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abel","family":"Mwanga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leanji","family":"Leonard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5938-5628","authenticated-orcid":false,"given":"Elifuraha W.","family":"Mkwizu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3618-2822","authenticated-orcid":false,"given":"Elichilia R.","family":"Shao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0367-5826","authenticated-orcid":false,"given":"Kajiru G.","family":"Kilonzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,31]]},"reference":[{"key":"e_1_2_13_1_2","unstructured":"World Health Organization World Malaria Report 2022 2022."},{"key":"e_1_2_13_2_2","unstructured":"U.S. President\u2019s malaria initiative U.S. President\u2019s Malaria Initiative Tanzania Mainland Malaria Operational Plan FY 2022 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Tanzania Ministry of Health, Community Development","author":"Omary M.","year":"2020","journal-title":"Gender, Elderly and Children National Malaria Control Programme"},{"key":"e_1_2_13_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12936-022-04301-8"},{"key":"e_1_2_13_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cqn.2016.04.004"},{"key":"e_1_2_13_15_2","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/4396108"},{"key":"e_1_2_13_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2011.379"},{"key":"e_1_2_13_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(15)00322-8"}],"container-title":["Case Reports in Infectious 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