{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T12:47:49Z","timestamp":1782478069912,"version":"3.54.5"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:00:00Z","timestamp":1782432000000},"content-version":"vor","delay-in-days":176,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Dermatological Medicine"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Primary cutaneous T\u2010cell lymphomas (pCTCLs) are a heterogeneous group of rare clonal T\u2010cell disorders, among which mycosis fungoides (MF) is the most common subtype. Several clinicopathologic variants of MF have been described, including poikilodermatous and hyperpigmented forms, with occasional overlap between variants. We report a 68\u2010year old man with a 25\u2010year history of slowly progressive, asymptomatic dark plaques involving the lower extremities and intergluteal fold consistent with overlapping hyperpigmented and poikilodermatous MF. Unlike the classically reticulated appearance of poikilodermatous MF, the lesions displayed extensive, sharply demarcated confluent hyperpigmentation. 18F\u2010FDG PET\/CT demonstrated no systemic involvement, although the cutaneous lesions displayed mild hypermetabolism. Histopathological examination revealed epidermotropic atypical lymphocytes with superficial dermal lymphohistiocytic infiltrates, vascular ectasia, erythrocyte extravasation, hemosiderin deposition, and dermal melanophages. Immunophenotypic studies supported the diagnosis of MF with monoclonal T\u2010cell receptor rearrangement. Disease staging was T2N0M0B0 (Stage IB). Given the longstanding indolent course, absence of symptoms, and lack of extracutaneous disease, a watch\u2010and\u2010wait strategy was adopted. Although hyperpigmentation may be observed in poikilodermatous MF, the unusually marked and confluent pigmentation in our patient exceeded the degree typically associated with poikiloderma alone, suggesting overlap with the hyperpigmented variant of MF. This case highlights the importance of careful clinicopathologic correlation in atypical pigmentary presentations of MF.<\/jats:p>","DOI":"10.1155\/crdm\/6659374","type":"journal-article","created":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T12:02:22Z","timestamp":1782475342000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Overlapping Hyperpigmented and Poikilodermatous Mycosis Fungoides"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7751-7601","authenticated-orcid":false,"given":"Joan","family":"Somja","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5240-4806","authenticated-orcid":false,"given":"Arjen F.","family":"Nikkels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,26]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1093\/bjd\/ljaf199"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.27735"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2020.0022"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1159\/000531979"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-021-00625-6"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-025-05547-4"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/2050313X251359024"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20175544"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1080\/10428194.2022.2043303"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/12034754241302822"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S541051"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-025-05169-3"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/ced\/llae237"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000002476"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-025-01511-1"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/bjd\/ljaf198"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/bjd\/ljaf367"}],"container-title":["Case Reports in Dermatological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crdm\/6659374","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crdm\/6659374","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crdm\/6659374","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T12:02:23Z","timestamp":1782475343000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crdm\/6659374"}},"subtitle":[],"editor":[{"given":"Semonti","family":"Nandi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/crdm\/6659374"],"URL":"https:\/\/doi.org\/10.1155\/crdm\/6659374","archive":["Portico"],"relation":{},"ISSN":["2090-6463","2090-6471"],"issn-type":[{"value":"2090-6463","type":"print"},{"value":"2090-6471","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-12-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"6659374"}}