{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T12:56:06Z","timestamp":1791550566142,"version":"4.3.4"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:00:00Z","timestamp":1791504000000},"content-version":"vor","delay-in-days":281,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Dermatological Medicine"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Protothecosis, a rare opportunistic infection caused by\n                    <jats:italic>Prototheca<\/jats:italic>\n                    species, achlorophyllous microalgae, is increasingly recognized but remains underdiagnosed due to its rarity and nonspecific clinical presentation. We report two cases of human protothecosis in Vietnam, occurring in a 63\u2010year\u2010old and 81\u2010year\u2010old female presenting with chronic, painful, ulcerative lesions on upper extremities. Despite initial misdiagnosis and empirical antifungal and antibacterial treatments, histopathological examination revealed characteristic\n                    <jats:italic>Prototheca<\/jats:italic>\n                    sporangia, leading to the definitive diagnosis. These cases underscore the importance of considering protothecosis in atypical cutaneous infections, particularly when patients fail to respond to empirical antibacterial or antifungal therapies, and highlight diagnostic and treatment challenges.\n                  <\/jats:p>","DOI":"10.1155\/crdm\/9136305","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T12:43:13Z","timestamp":1791549793000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cutaneous Protothecosis: Reported Human Cases in Vietnam and Diagnostic Challenges"],"prefix":"10.1155","volume":"2026","author":[{"given":"Thuy Thi Phan","family":"Nguyen","sequence":"first","affiliation":[{"name":"Ho Chi Minh City Hospital of Dermato-Venereology  Ho Chi Minh City Vietnam"},{"name":"Faculty of Medicine University of Health Sciences, Viet Nam National University  Ho Chi Minh City 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