{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T11:52:11Z","timestamp":1781610731988,"version":"3.54.5"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T00:00:00Z","timestamp":1781568000000},"content-version":"vor","delay-in-days":166,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Gastrointestinal Medicine"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Duodenal\u2010type follicular lymphoma (DTFL) is an uncommon and often indolent extranodal lymphoma that may be difficult to recognize when characteristic endoscopic or imaging findings are absent. We report a 60\u2010year\u2010old man evaluated for progressive fatigue, epigastric pain, and iron deficiency whose esophagogastroduodenoscopy showed normal\u2010appearing duodenal mucosa. Random duodenal biopsies revealed follicular lymphoma with morphology and immunophenotype consistent with follicular lymphoma, duodenal type, in the absence of systemic follicular lymphoma. Staging positron emission tomography\/computed tomography (PET\/CT) showed no focal duodenal fluorodeoxyglucose uptake but demonstrated equivocal low\u2010level uptake in mildly prominent mesenteric lymph nodes. Given unclear staging and persistent gastrointestinal symptoms affecting quality of life, the patient was treated with rituximab monotherapy. Follow\u2010up PET\/CT findings were consistent with complete metabolic response, and repeat duodenal biopsies showed no residual lymphoma. This case highlights the diagnostic value of random duodenal biopsy in unexplained iron deficiency and emphasizes the staging complexity of DTFL when PET\/CT findings are equivocal.<\/jats:p>","DOI":"10.1155\/crgm\/1030883","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T11:03:26Z","timestamp":1781607806000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Beyond the Surface: Duodenal\u2010Type Follicular Lymphoma Diagnosed Despite Normal\u2010Appearing Duodenal Mucosa and Absence of Focal Duodenal FDG 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