{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T11:37:31Z","timestamp":1784893051238,"version":"3.55.0"},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T00:00:00Z","timestamp":1746576000000},"content-version":"vor","delay-in-days":126,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Gastrointestinal Medicine"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>Peutz\u2013Jeghers syndrome (PJS) is a rare autosomal dominant disorder characterized by hamartomatous polyps in the gastrointestinal (GI) tract, pigmented mucocutaneous lesions, and an increased risk of cancer. We report a case of a 22\u2010year\u2010old male from Ethiopia who presented with recurrent abdominal pain and a history of surgery for bowel obstruction. Endoscopic evaluation revealed multiple polyps in the stomach, ileum, and colon, which were confirmed histopathologically as hamartomatous polyps. Mucocutaneous pigmentation and family history of GI symptoms and maternal breast cancer led to the diagnosis of PJS, despite the unavailability of genetic testing. The patient underwent therapeutic polypectomy and was advised on cancer surveillance. This case highlights the importance of recognizing and managing PJS in resource\u2010limited settings, emphasizing the need for early diagnosis and vigilant surveillance to prevent complications, especially when genetic testing may not be readily available.<\/jats:p>","DOI":"10.1155\/crgm\/3667487","type":"journal-article","created":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T17:19:16Z","timestamp":1746638356000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Peutz\u2013Jeghers Syndrome in a Young Ethiopian Male: A Case Report"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1640-1461","authenticated-orcid":false,"given":"Abate Bane","family":"Shewaye","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6726-5757","authenticated-orcid":false,"given":"Kaleb Assefa","family":"Berhane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,7]]},"reference":[{"key":"e_1_2_12_1_2","unstructured":"Peutz-Jeghers Syndrome: Clinical Manifestations Diagnosis and Management 2023 https:\/\/www.uptodate.com\/contents\/peutz-jeghers-syndrome-clinical-manifestations-diagnosis-and-management?search=Peutz-Jeghers%2520syndrome%2520%26source=search_result%26selectedTitle=1%7E53%26usage_type=default%26display_rank=1."},{"key":"e_1_2_12_2_2","volume-title":"StatPearls [Internet]","author":"Wu M.","year":"2023"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13205121"},{"key":"e_1_2_12_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2024.110117"},{"key":"e_1_2_12_5_2","unstructured":"Peutz-Jeghers Syndrome Medscape https:\/\/emedicine.medscape.com\/article\/182006-overview."},{"key":"e_1_2_12_6_2","first-page":"77","article-title":"Peutz-Jeghers Syndrome in a Zimbabwean","volume":"28","author":"Jena G. P.","year":"1982","journal-title":"Central African Journal of Medicine"},{"key":"e_1_2_12_7_2","first-page":"49","article-title":"Familial Polyposis in Two Ethiopians","volume":"32","author":"Mengesha B.","year":"1994","journal-title":"Ethiopian Medical Journal"},{"key":"e_1_2_12_8_2","first-page":"205","volume-title":"Current Surgical Therapy","author":"Apostolides G.","year":"2014"},{"key":"e_1_2_12_9_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.65931"},{"key":"e_1_2_12_10_2","first-page":"205","volume-title":"World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of the Digestive System","author":"Aaltonen L. A.","year":"2000"},{"key":"e_1_2_12_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000529799"}],"container-title":["Case Reports in Gastrointestinal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crgm\/3667487","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crgm\/3667487","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crgm\/3667487","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T15:27:56Z","timestamp":1772983676000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crgm\/3667487"}},"subtitle":[],"editor":[{"given":"Yoshifumi","family":"Nakayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/crgm\/3667487"],"URL":"https:\/\/doi.org\/10.1155\/crgm\/3667487","archive":["Portico"],"relation":{},"ISSN":["2090-6528","2090-6536"],"issn-type":[{"value":"2090-6528","type":"print"},{"value":"2090-6536","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2024-10-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"3667487"}}