{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T18:09:59Z","timestamp":1771438199710,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":33,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Gastrointestinal Medicine"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Pyogenic liver abscesses (PLAs) commonly result from hematogenous spread or biliary tract infections, most often due to cholecystitis or cholangitis.\n                      <jats:italic>Klebsiella pneumoniae<\/jats:italic>\n                      is a recognized pathogen in PLA and has been associated with underlying gastrointestinal malignancies, particularly colorectal cancer. While screening for malignancy is well established in cryptogenic\n                      <jats:italic>K. pneumoniae<\/jats:italic>\n                      liver abscess, its role when a clear biliary source is present is less well described.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>\n                      We report a 76\u2010year\u2010old man with a history of untreated hepatitis C and prior renal cell carcinoma who presented with right upper quadrant pain, weight loss, and leukocytosis. Imaging revealed a pericholecystic liver abscess with acute cholecystitis. The abscess was drained percutaneously, and cultures grew\n                      <jats:italic>K. pneumoniae<\/jats:italic>\n                      . Although imaging suggested a biliary source, colonoscopy was performed given the pathogen\u2019s known association with colorectal neoplasia. This revealed multiple large laterally spreading tumors, including a 30\u2010mm ascending colon lesion confirmed as well\u2010differentiated invasive adenocarcinoma on biopsy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      This case underscores the importance of considering colorectal cancer screening in patients with\n                      <jats:italic>K. pneumoniae<\/jats:italic>\n                      PLA, even when a biliary source is identified. Early endoscopic evaluation in such patients may facilitate timely diagnosis of occult malignancy and alter clinical management.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/crgm\/8835902","type":"journal-article","created":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T17:14:57Z","timestamp":1770138897000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association of Biliary Source\n                    <i>Klebsiella pneumoniae<\/i>\n                    Pyogenic Liver Abscess With Colon Adenocarcinoma: A Case Report"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4290-6188","authenticated-orcid":false,"given":"Dongmin","family":"Shin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1356-9699","authenticated-orcid":false,"given":"Sameer","family":"Kandhi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5632-3612","authenticated-orcid":false,"given":"Franklin","family":"Sosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5705-3275","authenticated-orcid":false,"given":"George","family":"Zacharia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3638-9495","authenticated-orcid":false,"given":"Harish","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,3]]},"reference":[{"key":"e_1_2_9_1_2","unstructured":"Facts and Statistics Colorectal Cancer Alliance https:\/\/colorectalcancer.org\/basics\/facts-and-statistics."},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/J.FOCUS.2024.100188"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.48218"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/J.MAYOCPIQO.2018.01.002"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/AJG.2009.614"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/J.1365-2036.2005.02487.X"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/J.JMII.2014.08.028"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000001871"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/J.1365-2036.2012.05212.X"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/J.DLD.2019.08.016"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i23.2948"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2012.03174.x"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2011.06851.x"}],"container-title":["Case Reports in Gastrointestinal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crgm\/8835902","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crgm\/8835902","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crgm\/8835902","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T17:15:11Z","timestamp":1771434911000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crgm\/8835902"}},"subtitle":[],"editor":[{"given":"Marcel Cerqueira Cesar","family":"Machado","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/crgm\/8835902"],"URL":"https:\/\/doi.org\/10.1155\/crgm\/8835902","archive":["Portico"],"relation":{},"ISSN":["2090-6528","2090-6536"],"issn-type":[{"value":"2090-6528","type":"print"},{"value":"2090-6536","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-03-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"8835902"}}