{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T16:33:51Z","timestamp":1789835631175,"version":"4.0.1"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T00:00:00Z","timestamp":1770249600000},"content-version":"vor","delay-in-days":35,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Hematology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Breast implant\u2013associated diffuse large B\u2010cell lymphoma (BIA\u2010DLBCL) is an extremely rare entity, often misdiagnosed as breast implant\u2013associated anaplastic large cell lymphoma (BIA\u2010ALCL). Unlike BIA\u2010ALCL, which is a T\u2010cell neoplasm, BIA\u2010DLBCL shows B\u2010cell immunophenotype and is frequently associated with Epstein\u2013Barr virus (EBV). Few cases have been reported and its optimal management remains unclear. We report the case of a 45\u2010year\u2010old woman with a history of breast augmentation surgery using textured silicone implants. She presented with left breast pain and deformity. Histopathological examination of the periprosthetic capsule revealed large atypical lymphoid cells, expressing CD20, CD19, PAX5, CD79a, and CD30, with EBV RNA positivity and absence of T\u2010cell markers. There was no capsular rupture. PET\u2010CT scanning showed hypermetabolic activity around the implant and ipsilateral axillary lymphadenopathy, without systemic involvement. A diagnosis of BIA\u2010DLBCL was retained. The patient underwent total capsulectomy without adjuvant therapy. At 30\u2010month follow\u2010up, she remains in complete clinical and radiological remission. BIA\u2010DLBCL is an increasingly reported entity which in most cases can be classified within the spectrum of fibrin\u2010associated large B\u2010cell lymphoma (FA\u2010LBCL). While surgical excision alone may be sufficient for localized disease, the rarity of this lymphoma highlights the urgent need for more comprehensive data, particularly long\u2010term survival outcomes, to refine classification and therapeutic recommendations.<\/jats:p>","DOI":"10.1155\/crh\/7488322","type":"journal-article","created":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T04:50:19Z","timestamp":1770353419000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Breast Implant\u2013Associated Epstein\u2013Barr Virus\u2010Positive Diffuse Large B\u2010Cell 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