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Rarely, it presents with pancytopenia and bone marrow changes resembling myelodysplastic syndrome\/neoplasm (MDS) and\/or acute myeloid leukemia (AML), complicating diagnosis and management. We present a case of a patient with severe folate deficiency, in the setting of normal vitamin B12 levels, who presented with hematologic and bone marrow findings initially suggestive of MDS\/AML that resolved with folate supplementation. This case highlights that the clinical and morphologic findings associated with severe folate deficiency can closely resemble those of high\u2010risk MDS or MDS\/AML. Careful diagnostic evaluation, including nutritional assessment, is essential to avoid the misclassification of reversible nutritional deficiencies as myeloid neoplasms requiring cytotoxic therapy.<\/jats:p>","DOI":"10.1155\/crh\/8212282","type":"journal-article","created":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T04:14:12Z","timestamp":1784952852000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Severe Folate Deficiency Mimicking Myelodysplastic Syndrome\/Acute Myeloid Leukemia: A Case 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