{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T18:22:09Z","timestamp":1772994129188,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T00:00:00Z","timestamp":1757548800000},"content-version":"vor","delay-in-days":253,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Hematology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>Intravascular large B\u2010cell lymphoma (IVLBCL) has a high mortality rate, partly due to its heterogeneous presentation and rarity. We present a case of a 73\u2010year\u2010old woman who came into the emergency room in need of fluid resuscitation, interpreted as septic shock. However, broad\u2010spectrum antibiotics gave no resolution, and no causative agent was found. Further physical examination showed proximal muscle weakness, Raynaud\u2019s phenomenon, and calcinosis cutis. During 3\u2009weeks of admission, vasopressor support was required continuously due to a capillary leak syndrome. The patient passed away. The underlying malignancy was only revealed at autopsy. To the best of our knowledge, this is the first case of IVLBCL with hypovolemic shock due to systemic capillary leak syndrome in combination with a wide range of immunological phenomena.<\/jats:p>","DOI":"10.1155\/crh\/9919411","type":"journal-article","created":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T08:47:17Z","timestamp":1757666837000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intravascular Large B\u2010Cell Lymphoma Presenting as Systemic Capillary Leak Syndrome With Immunological Phenomena: A Case Report"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3652-7472","authenticated-orcid":false,"given":"Helena M.","family":"van Dongen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3106-5734","authenticated-orcid":false,"given":"Bregje M.","family":"Koomen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3024-4889","authenticated-orcid":false,"given":"Jordy","family":"Jurgens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8720-3684","authenticated-orcid":false,"given":"Helen L.","family":"Leavis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,11]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2017-04-737445"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-153-2-201007200-00005"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.revmed.2021.05.012"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1403376"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ken422"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.5114\/reum.2020.96655"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2004.05177.x"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.21124"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-012-1548-5"},{"key":"e_1_2_11_10_2","first-page":"1189","article-title":"[Intravascular Large B-Cell Lymphoma Associated With Hypoalbuminemia and Hypoxemia]","volume":"41","author":"Yagita M.","year":"2000","journal-title":"Rinsho Ketsueki"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1309\/lmq1hhiw7zu9jttb"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.49.3986"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/neup.12175"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.3960\/jslrt.55.39"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.1080\/14397595.2016.1205798"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.160817"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.03112"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/6230138"},{"key":"e_1_2_11_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.02.007"},{"key":"e_1_2_11_20_2","doi-asserted-by":"publisher","DOI":"10.4172\/2155-9899.1000213"},{"key":"e_1_2_11_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.09.015"},{"key":"e_1_2_11_22_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-01-021253"}],"container-title":["Case Reports in Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crh\/9919411","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crh\/9919411","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crh\/9919411","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T15:05:11Z","timestamp":1772982311000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crh\/9919411"}},"subtitle":[],"editor":[{"given":"Kalyani","family":"Sen","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/crh\/9919411"],"URL":"https:\/\/doi.org\/10.1155\/crh\/9919411","archive":["Portico"],"relation":{},"ISSN":["2090-6560","2090-6579"],"issn-type":[{"value":"2090-6560","type":"print"},{"value":"2090-6579","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2024-09-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"9919411"}}