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Laboratory investigation revealed hepatitis C virus antibody positivity and an elevated hepatitis C virus ribonucleic acid level of 3.6 Log IU\/mL; therefore, direct\u2010acting antiviral therapy was initiated. Although the patient requested treatment for hepatitis C, managing her medication was difficult because of dementia, as she lived alone and had no family, which required her to take medication under supervision, even on holidays. After discharge, the patient was treated with glecaprevir hydrate and pibrentasvir for 8\u2009weeks by a hepatologist with biweekly visits to monitor adverse events. The hepatitis C virus ribonucleic acid test result was negative after 4\u2009weeks of treatment, and we asked her family physician to confirm a sustained virologic response. Collaboration among multiple specialists, both within and outside the hospital, is essential for facilitating the treatment of such patients.<\/jats:p>","DOI":"10.1155\/crhe\/5540732","type":"journal-article","created":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T10:43:52Z","timestamp":1769510632000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Case Report of Direct\u2010Acting Antiviral Therapy for Chronic Hepatitis C in a Patient With Dementia Treated in Collaboration With Multiple Specialists"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-1000-1808","authenticated-orcid":false,"given":"Tomoki","family":"Tanie","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kotaro","family":"Kanda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirotoshi","family":"Fujikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,27]]},"reference":[{"key":"e_1_2_13_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(12)61728-0"},{"key":"e_1_2_13_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/flgastro-2022-102373"},{"key":"e_1_2_13_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2015.07.003"},{"key":"e_1_2_13_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2016.07.035"},{"key":"e_1_2_13_5_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/146.6.1376"},{"key":"e_1_2_13_6_2","doi-asserted-by":"publisher","DOI":"10.2165\/00002512-200421120-00004"},{"key":"e_1_2_13_7_2","doi-asserted-by":"publisher","DOI":"10.2174\/1574884710666150812141525"},{"key":"e_1_2_13_8_2","doi-asserted-by":"publisher","DOI":"10.2165\/0002512-200825120-00005"},{"key":"e_1_2_13_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13269"},{"key":"e_1_2_13_10_2","doi-asserted-by":"publisher","DOI":"10.3390\/geriatrics7010008"},{"key":"e_1_2_13_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000920"},{"key":"e_1_2_13_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/jvh.13600"},{"key":"e_1_2_13_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/meg.0000000000002437"}],"container-title":["Case Reports in Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crhe\/5540732","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crhe\/5540732","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crhe\/5540732","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T01:30:04Z","timestamp":1769650204000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crhe\/5540732"}},"subtitle":[],"editor":[{"given":"Sreeja","family":"Dattachoudhury","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/crhe\/5540732"],"URL":"https:\/\/doi.org\/10.1155\/crhe\/5540732","archive":["Portico"],"relation":{},"ISSN":["2090-6587","2090-6595"],"issn-type":[{"value":"2090-6587","type":"print"},{"value":"2090-6595","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-06-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"5540732"}}