{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T16:49:04Z","timestamp":1772988544293,"version":"3.50.1"},"reference-count":5,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"vor","delay-in-days":90,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Hepatology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>Autoimmune hepatitis (AIH) is an immunological disorder of the liver characterized by hepatic necroinflammation due to the break in self\u2010tolerance to autoantigens. Many medications have been linked to drug induced AIH. A review of the literature reveals no documented association between Eltrombopag and AIH. Eltrombopag is a thrombopoietin receptor agonist used to help manage thrombocytopenia in immune mediated thrombocytopenia and chronic liver disease. Here, we present a case of a 59\u2010year\u2010old female with refractory thrombocytopenia who was started on Eltrombopag, and later developed AIH.<\/jats:p>","DOI":"10.1155\/crhe\/6637055","type":"journal-article","created":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T13:17:22Z","timestamp":1743513442000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["An Uncommon Association: Eltrombopag and Autoimmune Hepatitis"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1136-8789","authenticated-orcid":false,"given":"Fady","family":"Salama","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassnain","family":"Syed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nimish","family":"Thakral","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,1]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-011-1611-4"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23588"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2010.02.008"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31065"},{"key":"e_1_2_9_5_2","article-title":"Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases","author":"Clinical and Research Information on Drug-Induced Liver Injury","year":"2012","journal-title":"Autoimmune Hepatitis"}],"container-title":["Case Reports in Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crhe\/6637055","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/crhe\/6637055","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/crhe\/6637055","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T11:33:21Z","timestamp":1772969601000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/crhe\/6637055"}},"subtitle":[],"editor":[{"given":"Sreeja","family":"Dattachoudhury","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/crhe\/6637055"],"URL":"https:\/\/doi.org\/10.1155\/crhe\/6637055","archive":["Portico"],"relation":{},"ISSN":["2090-6587","2090-6595"],"issn-type":[{"value":"2090-6587","type":"print"},{"value":"2090-6595","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2023-08-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"6637055"}}