{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T14:53:16Z","timestamp":1781794396814,"version":"3.54.5"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:00:00Z","timestamp":1781740800000},"content-version":"vor","delay-in-days":168,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Cardiology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Heterotaxy syndrome\u2014polysplenia variant (left isomerism) with dextrocardia is a rare constellation of laterality defects characterized by left\u2010isomerism, multiple splenic nodules, and associated vascular and visceral anomalies. This report describes an adult Ethiopian woman who presented with nonspecific abdominal pain and was found to have imaging features diagnostic of heterotaxy (polysplenia variant).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>A 36\u2010year\u2010old Ethiopian female presented with a three\u2010day history of mild to moderate, nonradiating anterior abdominal pain. Physical examination revealed the apical impulse on the right and mild left upper quadrant tenderness. Contrast\u2010enhanced CT of the chest and abdomen demonstrated dextrocardia with the cardiac apex directed to the right, right\u2010sided aortic arch, interrupted inferior vena cava with azygos continuation, bilobed lungs consistent with left isomerism, multiple splenic nodules clustered in the left upper quadrant (polysplenia), and a short pancreas. Routine laboratory tests were unremarkable. The final diagnosis was heterotaxy syndrome\u2014polysplenia variant (left isomerism) with dextrocardia. The patient was managed conservatively for presumed costochondritis, counseled about her anatomical variation, advised to carry a medical alert card, and remained symptom\u2010free at two\u2010week follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Imaging features in this patient are most consistent with heterotaxy syndrome (polysplenia variant) rather than isolated situs inversus totalis. Clear, consistent diagnostic terminology (heterotaxy\u2014polysplenia variant with dextrocardia) is essential for accurate communication, appropriate counseling, and safe planning of future interventions. Recognition of such cases in underreported regions supports improved diagnostic awareness and tailored care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/cric\/6419535","type":"journal-article","created":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T14:14:12Z","timestamp":1781792052000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dextrocardia in Heterotaxy Syndrome (Polysplenia Variant) in a 36\u2010Year\u2010Old Ethiopian Woman: A Case Report and Literature Review"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2769-1772","authenticated-orcid":false,"given":"Kedir Negesso","family":"Tukeni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramadan Jemal","family":"Dekema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Kedir","family":"Shukri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jafer Yasin","family":"Mohammed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael Deyu","family":"Jima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merid Lemma","family":"Kebede","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,18]]},"reference":[{"key":"e_1_2_14_1_2","doi-asserted-by":"publisher","DOI":"10.1148\/rg.226025016"},{"key":"e_1_2_14_2_2","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.06.1179"},{"key":"e_1_2_14_3_2","doi-asserted-by":"publisher","DOI":"10.47338\/jns.v3.73"},{"key":"e_1_2_14_4_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2020.582350"},{"key":"e_1_2_14_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-017-1579-y"},{"key":"e_1_2_14_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.36073"},{"key":"e_1_2_14_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2021.01.790"},{"key":"e_1_2_14_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/2150135116682455"},{"key":"e_1_2_14_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-012-0247-2"},{"key":"e_1_2_14_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-020-01895-x"},{"key":"e_1_2_14_11_2","first-page":"1","article-title":"Kartagener Syndrome","volume":"35","author":"Guillot C. 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