{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T13:29:29Z","timestamp":1787059769248,"version":"build-2736575974"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:00:00Z","timestamp":1787011200000},"content-version":"vor","delay-in-days":229,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Dentistry"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Mandibular buccal bifurcation cyst (MBBC) is a rare inflammatory odontogenic cyst that frequently mimics chronic periapical pathosis, leading to potential misdiagnosis and unnecessary endodontic treatment. This case report describes the diagnosis and management of an MBBC associated with a vital mandibular left second molar (#18) in a healthy 16\u2010year\u2010old female, highlighting the value of pulp vitality testing, cone beam computed tomography (CBCT), and a custom 3D\u2010printed surgical guide for conservative management. The patient presented with buccal bony expansion and a 12\u2010mm periodontal probing depth with purulent exudate. The tooth responded normally to sensibility testing, with no history of caries or trauma. Interpretation of CBCT images revealed a well\u2010corticated mid\u2010root radiolucency with an expansile pattern and a well\u2010corticated buccal lesion originating from the buccal cortex with an intact lamina dura. A custom surgical guide fabricated from intraoral scans and CBCT data enabled precise cyst enucleation while preserving tooth vitality. Histopathology showed fibrovascular tissue with a dense chronic inflammatory infiltrate composed of lymphocytes, plasma cells, macrophages, and multinucleated giant cells. The diagnosis of an MBBC was based on clinical, radiographic, and histological findings, enabling preservation of the tooth with a minimally invasive approach. At the 1\u2010year follow\u2010up, the tooth remained vital, with normal probing depths and satisfactory bone healing on CBCT compared with the initial presentation. This case report emphasizes the need to consider MBBC in the differential diagnosis of radiolucent periapical lesions. Early detection, along with evidence\u2010based management and guided surgery, is essential to avoid misdiagnosis and unnecessary endodontic treatment.<\/jats:p>","DOI":"10.1155\/crid\/5146322","type":"journal-article","created":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T13:09:04Z","timestamp":1787058544000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Diagnosis and Guided Surgical Management of a Mandibular Buccal Bifurcation Cyst: A Case Report"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-6094-5147","authenticated-orcid":false,"given":"Adrian","family":"Reyes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ishaan","family":"Goel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2135-5300","authenticated-orcid":false,"given":"Steven","family":"Kaltman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6720-9923","authenticated-orcid":false,"given":"Yehuda","family":"Benjamin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4653-3799","authenticated-orcid":false,"given":"Catalina Mendez","family":"de la Espriella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2473-5098","authenticated-orcid":false,"given":"Rodrigo R.","family":"Amaral","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,18]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2010.01751.x"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(00)70098-9"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2020.01.003"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1590\/1807-3107bor-2021.vol35.0033"},{"key":"e_1_2_10_5_2","first-page":"712","article-title":"The Buccal Bifurcation Cyst: in Non-Surgical Treatment an Option?","volume":"64","author":"David L. 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