{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T04:51:33Z","timestamp":1791175893550,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T00:00:00Z","timestamp":1791072000000},"content-version":"vor","delay-in-days":276,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Dentistry"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The use of chlorhexidine as an adjunct to nonsurgical periodontal therapy has become a standard practice. However, its use presents some limitations in terms of treatment duration and patient compliance. For these reasons, clinical research is increasingly oriented towards alternative or complementary approaches aimed at supporting mechanical debridement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>This case report describes a patient affected by periodontitis who underwent nonsurgical periodontal therapy, with the application of ozone as an adjunct through Oria Bite appliance, an innovative customized tray fabricated through intraoral scanning, used for the targeted application of ozonated gel (GeliO3). Clinical periodontal parameters were evaluated at baseline, and at 1\u2010month and 6\u2010month follow\u2010up visits.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Preliminary clinical observations showed maintenance of periodontal stability, suggesting a possible role of the customized tray in supporting the control of gingival inflammation during the maintenance phase. The procedure was well\u2010tolerated by the patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The potential role of the customized device as a complementary approach in the adjunctive treatment of periodontitis deserves further evaluation in terms of cost\u2010effectiveness and workflow. Future controlled clinical studies with long\u2010term follow\u2010up are required to confirm the reproducibility of the observed results.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/crid\/6467447","type":"journal-article","created":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T03:59:47Z","timestamp":1791172787000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Novel Digital Tray for Customized Professional Ozonized Gel Delivery in Periodontal Maintenance: A Case Report"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1690-4904","authenticated-orcid":false,"given":"Maurizio","family":"Pascadopoli","sequence":"first","affiliation":[{"name":"Unit of Orthodontics and Pediatric Dentistry Section of Dentistry Department of Clinical Surgical Diagnostic and Pediatric Sciences University of Pavia  Pavia Italy  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Section of Dentistry Department of Clinical Surgical Diagnostic and Pediatric Sciences University of Pavia  Pavia Italy  unipv.eu"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2760-0124","authenticated-orcid":false,"given":"Andrea","family":"Scribante","sequence":"additional","affiliation":[{"name":"Unit of Orthodontics and Pediatric Dentistry Section of Dentistry Department of Clinical Surgical Diagnostic and Pediatric Sciences University of Pavia  Pavia Italy  unipv.eu"},{"name":"Service of Oral Pathology Section of Dentistry Department of Clinical Surgical Diagnostic and Pediatric Sciences University of Pavia  Pavia Italy  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