{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T20:09:09Z","timestamp":1773000549447,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T00:00:00Z","timestamp":1749686400000},"content-version":"vor","delay-in-days":162,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Dentistry"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>Palisaded encapsulated (solitary circumscribed) neuroma (PEN) is a benign nerve sheath tumor, considered a reactive rather than a neoplastic lesion, predominantly found in the head and neck skin and oral mucosa. In the lip regions, less than 20 cases of PEN have been reported, and the differential diagnosis is a challenge. We present a 40\u2010year\u2010old male with a long\u2010standing asymptomatic nodule on the lower lip, causing significant aesthetic discomfort, and a literature review of this tumor in the lips. After surgical excision, the histopathological analysis associated with immunohistochemical markers was essential for establishing the PEN diagnosis in the lower lip. Although rare, the PEN in the lip region can cause significant patient aesthetic discomfort, and histopathological analysis is crucial to distinguish this benign neural tumor from other long\u2010standing lesions in the vermillion of the lips.<\/jats:p>","DOI":"10.1155\/crid\/9705734","type":"journal-article","created":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T01:49:05Z","timestamp":1749779345000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Palisaded Encapsulated (Solitary Circumscribed) Neuroma Affecting the Lip Aesthetics: Case Report and Literature Review"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6991-209X","authenticated-orcid":false,"given":"Kaique Alberto","family":"Preto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9976-9511","authenticated-orcid":false,"given":"Gabriela","family":"Lopes-Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1286-5410","authenticated-orcid":false,"given":"Cl\u00e9verson Teixeira","family":"Soares","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Paula Moura Martins","family":"Delazari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4628-7129","authenticated-orcid":false,"given":"Denise Tostes","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,12]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1972.01620150051016"},{"key":"e_1_2_10_2_2","volume-title":"Solitary Circumscribed Neuroma. 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